Introduction -- Composition and structure -- Production techniques -- Characterization -- Physicochemical stability.

What are lipid nanoparticles?Âȯw are they structured?Âȯw are they formed? What techniques are best to characterize them?Âȯw great is their potential as drug delivery systems?These questions and more are answered in this comprehensive and highly readable work on lipid nanoparticles. This work sets out to provide the reader with a clear andÂ{u5BA4}erstandableÂ{u5BA4}erstanding of the current practices in formulation, characterization and drug delivery of lipid nanoparticles. AÂ{u3BED}prehensive description ofÂ{u4A25} current understanding of synthesis, characterization, stability optimization and drug incorporation of solid lipid nanoparticles is provided. Nanoparticles have attracted great interest over the past few decades with almost exponential growth in their research and application. Their small particle size and subsequent high surface area make them ideal in many uses, but particularly as drug carrier systems.Â{uE86E}noparticles made from lipids are especially attractive because of their enhanced biocompatibility imparted by the lipid. TheÂ{u7BF2}k provides a detailed description of the types of lipid nanoparticles available (e.g. SLN, NLC, LDC, PLN) and how they range from imperfect crystalline to amorphous in structure.Â{u3D72}rrent thoughts on where drugs are situated (e.g. in the core, or at the interface) and how this can be manipulated are discussed.The many techniques for production, including the authorâ€{u382F}wn variant of microwave heating, are fully discussed.Â{u4963}hniques for measuring arguably the most important characteristics of particle size and polydispersity are discussed, along with techniques to measure crystallinity, shape and drug capacity.Â{u01A9}nally, a full chapter on techniques for measuring stability, both in the absence and presence of drugs, is discussed, along with suggestions on how to optimize that stability. ThisÂ{u7BF2}k appealsÂ{u4BE0}students of colloid science, practitioners of research into drug delivery and academics alike.