Capillary Electrophoresis-Mass Spectrometry : Therapeutic Protein Characterization / edited by James Q. Xia, Lichao Zhang
Contributor(s): Xia, James Q., editor literario
| Zhang, Lichao, editor literario
Material type: 
E-bookPublisher: Cham : Springer International Publishing, 2016Description: 1 recurso en línea (IX, 74 p.) : 28 ilustraciones, 21 ilustraciones en color.ISBN: 9783319462400.Subject: Espectrometría de masas | Proteínas | MicroscopiaOnline resources: Click here to access online
| Item type | Current library | Collection | Call number | Copy number | Status | Date due | Barcode | Item holds | |
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LIBRO-E NO PRÉSTAMO
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Madrid Digital Acceso Electrónico (UEM) | Ciencias de la Salud | QP519.9.M3 C375 2016 EB (Browse shelf(Opens below)) | .i11603756 | Acceso electrónico | eBOOK .i11603756 |
Introduction to Capillary Electrophoresis{u2014}Mass Spectrometry -- Coated Capillaries for CE-MS of Therapeutic Protein -- Intact Mass Analysis of Monoclonal Antibodies by Capillary Electrophoresis-Mass Spectrometry -- Separation and Characterization of Proteins and Peptides in Biological Fluids using CE-MS -- Host Cell Protein Analysis using CE-MS -- Antibody PTM Analysis using CE-MS -- Characterization of Intact Therapeutic Proteins and Protein Subunits using CE-MS Platform
This book covers the latest developments in capillary electrophoresis-mass spectrometry for the analysis of therapeutic proteins. The application of capillary electrophoresis-mass spectrometry (CE-MS) coupling technology in the analysis of recombinant therapeutic proteins is detailed thoroughly. Specific topics include recent developments in coupling capillary electrophoresis with mass spectrometry for the quality control of monoclonal antibody therapeutics, top-down analysis of monoclonal antibody using the CE-MS platform, and detection of host cell protein impurities. Comprehensive characterization of antibody-drug conjugates (ADCs) by coupling capillary electrophoresis with mass spectrometry is also covered. This is an ideal book for scientists in the life science and biopharmaceutical industry who are working on characterizing the PTMs of monoclonal antibodies, as well as graduate students and researchers in the separation science and biological mass spectrometry fields
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