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Behçet's disease : from genetics to therapies / edited by Yoshiaki Ishigatsubo

Contributor(s): Ishigatsubo, Yoshiaki, editor literario
Material type: materialTypeLabelE-bookPublisher: Tokyo : Springer, cop. 2015Description: 1 recurso en línea (IX, 176 p.) : il..ISBN: 9784431544876.Subject: Síndrome de BehçetDDC classification: 616.723 Online resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources Summary: This book, besides reviewing basic and clinical aspects of BehÃ{u00A7}et's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of BehÃ{u00A7}et's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- BehÃ{u00A7}et's disease. BehÃ{u00A7}et's Disease:Â{u01B2}om Genetics to Therapies Â{u0CAF}vides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in BehÃ{u00A7}et's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.
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Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud RC122.B4 B44 2015 EB (Browse shelf(Opens below)) .i11580094 Acceso electrónico eBOOK .i11580094
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This book, besides reviewing basic and clinical aspects of BehÃ{u00A7}et's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of BehÃ{u00A7}et's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- BehÃ{u00A7}et's disease. BehÃ{u00A7}et's Disease:Â{u01B2}om Genetics to Therapies Â{u0CAF}vides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in BehÃ{u00A7}et's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.

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