Behçet's disease : from genetics to therapies
Behçet's disease : from genetics to therapies
edited by Yoshiaki Ishigatsubo
- Tokyo Springer cop. 2015
- 1 recurso en línea (IX, 176 p.) il.
This book, besides reviewing basic and clinical aspects of BehÃet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of BehÃet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- BehÃet's disease. BehÃet's Disease:Âom Genetics to Therapies Âvides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in BehÃet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.
9784431544876
Síndrome de Behçet
RC122.B4 / 2015 EB
616.723
This book, besides reviewing basic and clinical aspects of BehÃet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of BehÃet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- BehÃet's disease. BehÃet's Disease:Âom Genetics to Therapies Âvides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in BehÃet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.
9784431544876
Síndrome de Behçet
RC122.B4 / 2015 EB
616.723