Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development : A Focus on Early Phase Clinical Studies / edited by Andrew J. Krentz, Lutz Heinemann, Marcus Hompesch.
Contributor(s): SpringerLink (Online service)
| Krentz, Andrew J., editor literario | Heinemann, Lutz, editor literario | Hompesch, Marcus, editor literario
Material type: 
E-bookPublisher: London : Springer, 2015Description: 1 recurso en línea (XII, 312 páginas) : 76 ilustraciones, 39 ilustraciones en color.ISBN: 9781447149200.Subject: Tecnología farmacéutica | Diabetes | FarmacologíaOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)
| Item type | Current library | Collection | Call number | Copy number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|---|---|
LIBRO-E NO PRÉSTAMO
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Madrid Digital Acceso Electrónico (UEM) | Ciencias de la Salud | RM301.25 T736 2015 EB (Browse shelf(Opens below)) | .i11573089 | Acceso electrónico | eBOOK .i11573089 |
1. Review of physiology/pathophysiology -- 2. Methods for assessing insulin action in humans -- 3. Assessment of insulin secretion -- 4. Measurement of ectopic fat in liver and muscle using magnetic resonance spectroscopy -- 5. Isotopic tracers for theÂ{uD961}surement of metabolic flux -- 6. Measuring food intake inÂ{u3B29}nical drug development -- 7. Measurement of energy expenditure -- 8. Assessment of body composition -- 9.Â{u0073}sessment of cardiovascular safety of new diabetes drugs.
This book aims to aid the selection of the most appropriate techniques for use in earlyÂ{u0A21}se (1 and 2) clinicalÂ{u3D35}dies of new drugs for diabetes, obesity, and related cardiometabolic disease. Clinical research methods for assessing theÂ{u0A21}rmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycaemicÂ{u3B21}mp technique,Â{u8876}e become well-established in proof-of-mechanism studies; however, selection of the best techniques is by no means straightforward. This bookÂ{u7A6C}lÂ{u1A64} the understanding ofÂ{u4A25} needÂ{u6BF2} newÂ{u0A21}rmacotherapiesÂ{u6BF2}Â{u4E70}e 1 diabetes, type 2 diabetes, and obesity and the molecular targets of drugs currently in development.Â{u2805}EmergingÂ{u4963}hnologies including the omics disciplinesÂ{u1CA5} considered togetherÂ{u7A74}h practical and ethicalÂ{u9CF3}ues ofÂ{u5872}ly phase clinicalÂ{u4CA9}als in subjects with cardiometabolic disorders. Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug DevelopmentÂ{u2837}will be of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.
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