Glioma Signaling
Glioma Signaling
edited by Jolanta Barańska
- Dordrecht, Netherlands Springer International Publishing 2013
- 1 recurso en línea (X, 227 p.) 39 ilustraciones, 27 ilustraciones en color
- Advances in Experimental Medicine and Biology 986 0065-2598 .
Introduction to Purinergic Signalling in the Brain / Adenosine Signaling in Glioma Cells / Cross-Talk in Nucleotide Signaling in Glioma C6 Cells / Calcium Signaling in Glioma Cells -- The Role of Nucleotide Receptors / Purinergic Signaling in Glioma Progression / Cytoskeleton and Nucleotide Signaling in Glioma C6 Cells / Signaling Determinants of Glioma Cell Invasion / Receptor Tyrosine Kinases: Principles and Functions in Glioma Invasion / TGF Beta Signaling and Its Role in Glioma Pathogenesis / STAT Signaling in Glioma Cells / Cannabinoid Signaling in Glioma Cells / Geoffrey Burnstock -- Stefania Ceruti and Maria P. Abbracchio -- Dorota Wypych and Jolanta Barańska -- Dorota Wypych and Paweł Pomorski -- Elizandra Braganhol, Márcia Rosângela Wink, Guido Lenz and Ana Maria Oliveira Battastini -- Wanda Kłopocka, Jarosław Korczyński and Paweł Pomorski -- Aneta Kwiatkowska and Marc Symons -- Mitsutoshi Nakada, Daisuke Kita, Lei Teng, Ilya V. Pyko and Takuya Watanabe, et al. -- Bozena Kaminska, Marta Kocyk and Magdalena Kijewska -- Karolina Swiatek-Machado and Bozena Kaminska -- Aleksandra Ellert-Miklaszewska, Iwona Ciechomska and Bozena Kaminska
Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy.
9789400747197
10.1007/978-94-007-4719-7 doi
Cerebro--Tumores
Glioma
Sistema nervioso--Tumores
RC280.B7 / G55 2013 EB
610
Introduction to Purinergic Signalling in the Brain / Adenosine Signaling in Glioma Cells / Cross-Talk in Nucleotide Signaling in Glioma C6 Cells / Calcium Signaling in Glioma Cells -- The Role of Nucleotide Receptors / Purinergic Signaling in Glioma Progression / Cytoskeleton and Nucleotide Signaling in Glioma C6 Cells / Signaling Determinants of Glioma Cell Invasion / Receptor Tyrosine Kinases: Principles and Functions in Glioma Invasion / TGF Beta Signaling and Its Role in Glioma Pathogenesis / STAT Signaling in Glioma Cells / Cannabinoid Signaling in Glioma Cells / Geoffrey Burnstock -- Stefania Ceruti and Maria P. Abbracchio -- Dorota Wypych and Jolanta Barańska -- Dorota Wypych and Paweł Pomorski -- Elizandra Braganhol, Márcia Rosângela Wink, Guido Lenz and Ana Maria Oliveira Battastini -- Wanda Kłopocka, Jarosław Korczyński and Paweł Pomorski -- Aneta Kwiatkowska and Marc Symons -- Mitsutoshi Nakada, Daisuke Kita, Lei Teng, Ilya V. Pyko and Takuya Watanabe, et al. -- Bozena Kaminska, Marta Kocyk and Magdalena Kijewska -- Karolina Swiatek-Machado and Bozena Kaminska -- Aleksandra Ellert-Miklaszewska, Iwona Ciechomska and Bozena Kaminska
Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy.
9789400747197
10.1007/978-94-007-4719-7 doi
Cerebro--Tumores
Glioma
Sistema nervioso--Tumores
RC280.B7 / G55 2013 EB
610