000			03477nam a22003855i 4500
001			99936
003			DE-He213
005			20230110040157.0
007			cr nn 008mamaa
008			180112s2018 si | s |||| 0|eng d
020			_a9789811048432 _9
024	7		_a10.1007/978-981-10-4843-2 _2doi
040			_aES-MaUEC _bspa
050		4	_aRC848.H44 2018 EB
245	1	0	_aHepatitis B Virus and Liver Disease _cedited by Jia-Horng Kao, Ding-Shinn Chen.
264		1	_aSingapore _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XVII, 360 páginas 40 ilustraciones, 29 ilustraciones a color)
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
505	0		_aLife cycle and molecular virology -- Unmet needs in basic research: in vitro and in vivo models -- Immunopathogenesis -- Epidemiology and natural history -- Hepatitis B vaccination -- Viral factors and disease progression -- Host genetic factors and disease progression -- Molecular carcinogenesis of HCC -- Interferon therapy and long-term outcomes -- Nucleotide therapy and long-term outcomes -- Combination therapy -- Treatment of patients with HCV, HDV or HIV co-infection -- Management of children and pregnant women -- Management of patients with immunosuppressive therapy -- Towards an HBV cure: discovery of novel agents -- Others: occult HBV infection.
520	3		_aThis book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in management of patients with chronic HBV infection and investigation HBV infection.
650		7	_aHepatitis B _9158777 _2embne
650		7	_aHígado _xEnfermedades _9169917 _2embne
700	1		_aKao, Jia-Horng _eeditor literario _0http://id.loc.gov/authorities/names/n2018184252 _0http://viaf.org/viaf/57152986684212671296
700	1		_aChen, Ding-Shinn _eeditor literario _0http://id.loc.gov/authorities/names/n2016188599 _0http://viaf.org/viaf/112933654
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _0http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9789811048425
776	0	8	_iEdición impresa: _z9789811048449
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-10-4843-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aMedicine (Springer-11650)
988			_aSpringer_Medicine_2018
998			_b02/2019 _dz _ef _feng _ggw _h0
999			_c99936 _d99936 _x1