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020 _a9781493975051
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050 4 _aQL966
_b2017 EB
245 0 4 _aThe biology of mammalian spermatogonia
_cJon M. Oately, Michael D. Griswold, editors.
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
500 _a
505 0 _aPART 1: Spermatogenesis in Mammals -- Chapter 1: Organization of the Seminiferous Epithelium and the Cycle, and Morphometric Description of Spermatogonial Subtypes (Rodents and Primates) -- PART 2: Postnatal Development of the Spermatogonial Population -- Chapter 2: Transition of Prenatal Prospermatogonia to Postnatal Spermatogonia -- Chapter 3: Setting the Stage: The First Round of Spermatogenesis -- PART 3: Spermatogonial Stem Cells -- Chapter 4: Defining the Phenotype and Function of Mammalian Spermatogonial Stem Cells -- Chapter 5: The Biology of Mammalian Spermatogonia: Regulation of Spermatogonial Stem Cell Maintenance and Self-renewal -- PART 4: Spermatogonial Differentiation -- Chapter 6: Role of Retinoic Acid Signaling in the Differentiation of Spermatogonia -- Chapter 7: Gonadotropin and Steroid Hormone Control of Spermatogonial Differentiation -- PART 5: Genome Integrity of Spermatogonia -- Chapter 8: Frequency of Human Disease Mutations and Spermatogonial Stem Cell Function -- Chapter 9: The Spermatogonial Stem Cell and the Environment -- Chapter 10: Testicular Germ Cell Tumors and Teratomas -- PART 6: Tools to Study Spermatogonial Biology -- Chapter 11: Transplantation and Culture of Spermatogonial Stem Cells -- Chapter 12: In Vitro Differentiation of Spermatogonia -- PART 7: Therapeutic Potentials and Applications of Spermatogonia -- Chapter 13: Fertility Preservation in Cancer Patients -- Chapter 14: Application of Spermatogonial Transplantation in Agricultural Animals. .
520 3 _aThis book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational information that will be useful for seasoned researchers in the field of germ cell biology as well as investigators entering the area. Looking to the future, the editors predict that the foundational information provided in this book -- combined with the advent of new tools and budding interests in use of non-rodent mammalian models -- will produce another major advance in knowledge regarding the biology of spermatogonia over the next decade. In particular, we anticipate that the core molecular machinery driving different spermatogonial states in most, if not all, mammals will be described fully, the extrinsic signals emanating from somatic support cell populations to influence spermatogonial functions will become fully known, and the capacity to derive long-term cultures of SSCs and transplant the population to regenerate spermatogenesis and fertility will become a reality for higher order mammals. .
588 0 _aVendor-supplied metadata.
988 _aEBOOK, EBSPRINGER_2017
650 7 _aBiología
_2embne
_9138150
700 1 _aGriswold, Michael D.,
_eeditor literario
700 1 _aOatley, Jon M.,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-1-4939-7505-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2018
_dz
_e-
_zSI