000			03655cam a2200409Mu 4500
999			_c96712 _d96712 _x1
001			96712
003			ES-MaUEC
005			20230102112807.0
006			m o d
007			cr cnu---unuuu
008			171125s2017 xx o 000 0 eng d
020			_a3319675915 _q(electronic bk.)
020			_a9783319675916 _q(electronic bk.)
020			_z3319675907
020			_z9783319675909
040			_aEBLCP _beng _epn _cEBLCP _dOCLCO _dYDX _dN$T _dGW5XE _dVT2 _dOCLCQ _dAZU _dUPM _dIOG _dOCLCF _dUAB _dMERER _dES-MaUEC _bspa
050		4	_aRC254.6 _b2017 EB
100	1		_aTelerman, Adam _9677368
245	1	0	_aTCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2017
300			_a1 recurso en línea (314 páginas)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aResults and Problems in Cell Differentiation _vv. 64
500			_a
505	0		_a1 Introduction: How we encountered TCTP and our purpose in studying it -- 2 Structural insights into TCTP and its interactions with ligands and proteins -- 3 Structure-Function relationship of TCTP -- 4 The Translational Controlled Tumour Protein TCTP: Biological Functions and Regulation -- 5 Current understanding of the TCTP interactome -- 6 Role and fate of TCTP in protein degradative pathways -- 7 Roles of the Translationally Controlled Tumor Protein (TCTP) in plant development -- 8 Function of Translationally controlled tumor protein in organ growth: Lessons from Drosophila studies -- 9 Translationally controlled tumor protein (TCTP/HRF) present in animal venoms -- 10 Tctp in Neuronal Circuitry Assembly -- 11 Elusive role of TCTP protein and mRNA in cell cycle and cytoskeleton regulation -- 12 TCTP protein and the cellular response to ionizing radiation-induced DNA damage -- 13 TCTP has a crucial role in the different stages of Prostate Cancer malignant progression -- 14 Role of TCTP for cellular differentiation and cancer therapy -- 15 Targeting TCTP with sertraline and thioridazine in cancer treatment -- 16 . History of Histamine Releasing Factor (HRF)/TCTP including a Potential Therapeutic Target in Asthma and Allergy.
520	3		_aThis book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development. It begins by discussing the structure/function of TCTP, before exploring its role in different species ranging from plants to Drosophila and covering fields such as development, the cytoskeleton, cell division, DNA fragility and apoptosis. In turn, the book's final section is devoted to the role of TCTP in disease, namely asthma and diverse cancers, and ultimately as a target for the treatment of malignancies. What is the common denominator between all these processes and why is TCTP necessary in order for them to occur, even in the worst case such as cancer? The book seeks to provide meaningful answers to this and other key questions. Presenting a broad and revealing view on the topic, it offers an informative guide for scientists and students alike.
588	0		_aVersión impresa
988			_aEBOOK, EBSPRINGER_2017
650		7	_aProteínas _2embne _9139861
700	1		_aAmson, Robert _9677369
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-67591-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI