000			06455cam a2200421Ii 4500
988			_aSpringer_Medicine_2017
999			_c96710 _d96710 _x1
001			96710
003			ES-MaUEC
005			20230102112807.0
006			m o d
007			cr |n|||||||||
008			170810s2017 enk ob 001 0 eng d
020			_a1447152441
020			_a144715245X
020			_a9781447152446
020			_a9781447152453
020			_z1447152441
020			_z9781447152446 _q(print)
040			_aCOO _beng _erda _cCOO _dNJR _dUAB _dOCLCF _dYDX _dEBLCP _dN$T _dGW5XE _dDKU _dAZU _dUPM _dMERER _dGZM _dIOG _dOCLCO _dOCLCA _dOH1 _dOCLCO _dES-MaUEC _bspa
050		4	_aRC681 _b2017 EB
245	0	0	_aPhysiological assessment of coronary stenoses and the microcirculation _cedited by Javier Escaned, Justin Davies.
264		1	_aLondon _bSpringer International Publishing _c2017
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
500			_a
504			_aIncluye referencias bibliográficas e índice
505	0		_aFOREWORD -- INTRODUCTION -- Part 1. The Coronary Circulation in Health and Disease -- STRUCTURE AND PHYSIOLOGY OF THE CORONARY CIRCULATION -- A historical perspective on coronary circulation -- The anatomy of epicardial ,coronary arteries and veins -- The structure of transmural vessels and coronary microcirculation -- Regulation of coronary blood flow -- Myocardial metabolism and blood supply -- Coronary capacitance and the myocardial pump model -- Extravascular compression and vascular waterfalls -- Extrinsic neural control of blood flow -- Hemodynamic effects of epicardial stenoses -- Modification of shear stress by stenoses -- Phasic characteristics in coronary blood flow -- PATHOLOGICAL CHANGES IN CORONARY CIRCULATION -- Epicardial coronary stenosis -- Microvascular remodelling -- Microvascular obstruction -- Extravascular compression of the microcirculation -- Endothelial dysfunction -- Collateral development -- EFFECT OF SPECIFIC PATHOLOGIES ON EPICARDIAL VESSELS AND THE MICROCIRCULATION -- Hypertension and left ventricular hypertrophy -- Diabetes -- Dyslipidemia -- Atherosclerosis. Acute coronary syndromes -- Atherosclerosis. Chronic ischemia -- Acute and chronic effects of percutaneous coronary interventions -- Valvular heart disease -- Part II. Invasive Assessment of the Coronary Circulation in the Catheterization Laboratory -- FRACTIONAL FLOW RESERVE (FFR) -- Understanding fractional flow reserve -- Current evidence on FFR as a clinical tool -- Application of fractional flow reserve to specific stenosis subsets -- INSTANTANEOUS WAVE FREE RATIO (iFR) -- Physiological principles of iFR -- Validation of iFR. Clinical registries -- Application of iFR in clinical scenarios -- CORONARY FLOW RESERVE -- Understanding coronary flow reserve -- Use of Doppler-tipped guidewires to calculate coronary flow reserve -- Relative and adjusted coronary flow reserve -- Use of the thermodilution principle to calculate coronary flow reserve -- INDICES OF CORONARY RESISTANCE -- Understanding indices of coronary resistance -- Stenosis resistance estimated from pressure-flow relationships -- Myocardial resistance estimated with thermodilution and pressure -- Microcirculatory resistance calculated from intracoronary pressure and Doppler -- Integration of pressure and flow indices of coronary stenosis severity -- WAVE INTENSITY ANALYSIS -- Understanding wave intensity analysis -- Wave patterns in coronary flow in health and disease -- Changes in WIA coronary patterns during trans-arterial valve implantation -- ASSESSMENT OF ENDOTHELIAL DYSFUNCTION -- Understanding endothelial modulation of vascular tone -- Assessment of endothelial dysfunction with acetylcholine challenge -- Other methods to assess endothelial dysfunction -- RESEARCH MODELS -- Relevant differences between coronary circulation in human and experimental animal models -- Computerised fluid dynamics applied to modelling of coronary circulation.
520	3		_aSince the introduction of coronary angiography, a key technique in understanding coronary artery disease, a number of paradigms regarding its study and interpretation have taken place. Following an emphasis on improved angiographic and subsequent intracoronary imaging techniques, functional assessment of coronary circulation has demonstrated to have major implications for diagnosis and treatment of coronary artery disease. Fractional flow reserve, a pressure derived index of stenosis severity, constitutes the best example of the current importance of physiological assessment in clinical practice. However, the acceptance of FFR by cardiologists contrasts with important voids in knowledge on the basic principles of coronary physiology and of other available techniques that, as an alternative to FFR, allow a more comprehensive assessment of coronary circulation. This is particularly noticeable in the assessment of microcirculation, an unavoidable compartment of coronary circulation that is frequently affected in acute coronary syndromes of in the presence of cardiovascular risk factors or non-coronary heart disease. A deeper understanding of the relationship between epicardial vessel and microcirculatory involvement has started with the advent of newer imaging techniques like invasive optical coherence tomography, and non-invasive CT and NMR techniques. This book aims to be an indispensable tool for clinicians and researches in the field of coronary artery disease. It provides a balanced, comprehensive review of anatomy, physiology and available techniques, discusses both the diagnosis of epicardial vessel and microcirculatory disease, the impact of different diseases at different levels of coronary circulation, and the best way to address a separate or combined assessment of different levels of coronary circulation.
588			_aDescription based on online resource, title from PDF title page (SpringerLink, viewed January 10, 2018).
650		7	_9138557 _aCardiología _2fast _0(OCoLC)fst00847121 _0LocalZ
700	1		_aDavies, Justin, _eeditor literario
700	1		_aEscaned, Javier, _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-1-4471-5245-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI