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020 _a9789811065262
_q(electronic bk.)
020 _a9811065268
_q(electronic bk.)
020 _z9789811065255
020 _z981106525X
040 _aYDX
_beng
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_bspa
050 4 _aQL938.M4
_b2017 EB
100 1 _aLiang, Xin.
245 1 0 _aMechanosensory transduction in Drosophila melanogaster
_cXin Liang, Landi Sun, Zhen Liu.
264 1 _aSingapore
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
490 0 _aSpringerBriefs in biochemistry and molecular biology
500 _a
_bSpringer Biomedical and Life Sciences eBooks 2017 English+International
504 _aIncluye referencias bibliográficas
505 0 _a""Preface""; ""Acknowledgments""; ""Contents""; ""Chapter 1: Overview of Mechanosensory Transduction""; ""1.1 Mechanosensory Transduction""; ""1.1.1 Sensory Transduction""; ""1.1.2 Mechanosensory Transduction in Physiology""; ""1.1.3 Dysfunction of Mechanotransduction in Diseases""; ""1.1.4 Summary""; ""1.2 Model I: Bacteria""; ""1.2.1 Mechanotransduction in Bacteria""; ""1.2.2 Mechanosensitive Channels (Msc) (Kung et al. 2010)""; ""1.2.3 The Surface Attaching Apparatus (Persat et al. 2015; Persat 2017)""; ""1.3 Model II: Touch-Sensitive Neurons in C. elegans""
505 8 _a""1.3.1 Mechanosensation in C. elegans""""1.3.2 A Good Animal Model""; ""1.3.3 Mechanosensory Neurons in C. elegans""; ""1.3.4 The Transduction Apparatus in C. elegans Touch Receptors (Goodman 2006; Lumpkin et al. 2010)""; ""1.4 Model III: Inner Ear Hair Cells""; ""1.4.1 Function and Structure of the Hair Cells (Gillespie and Muller 2009)""; ""1.4.2 Mechanotransduction Apparatus in Hair Cells""; ""1.5 Summary""; ""References""; ""Chapter 2: â#x80;#x9C;Gating-Springâ#x80;#x9D; Model for Mechanotransduction""; ""2.1 A Minimal Mechanotransduction Apparatus""; ""2.1.1 The Processer""
505 8 _a""2.1.2 The Responder""""2.1.3 Examples""; ""2.2 The â#x80;#x9C;Gating-Springâ#x80;#x9D; Model""; ""2.2.1 Overview""; ""2.2.2 The Simple Mechanical Description""; ""2.2.3 Model Predictions: Sensitivity and Dynamic Range""; ""2.2.4 Functional Implications""; ""2.2.5 Molecular Basis""; ""References""; ""Chapter 3: Mechanoreceptors in Drosophila melanogaster""; ""3.1 Overview of Fly Mechanoreceptors""; ""3.2 Type I Mechanoreceptors""; ""3.2.1 Bristle Sensilla""; ""3.2.2 Campaniform Sensilla""; ""3.2.3 Chordotonal Organ""; ""3.2.4 Ciliated Mechanoreceptors in Fly Larvae""; ""3.3 Type II Mechanoreceptors""
505 8 _a""3.3.1 Class I da Neuron""""3.3.2 Class II da Neuron""; ""3.3.3 Class III da Neuron""; ""3.3.4 Class IV da Neuron""; ""3.4 Summary""; ""References""; ""Chapter 4: Mechanotransduction in Drosophila Mechanoreceptors""; ""4.1 Overview of Fly Mechanotransduction""; ""4.2 Bristle Receptor""; ""4.2.1 Bristle Deflection""; ""4.2.2 Dendritic Tip and the Supporting Structures""; ""4.3 Campaniform Receptor""; ""4.3.1 Cuticle Deformation""; ""4.3.2 Dendritic Tip and the Supporting Structures""; ""4.3.3 Molecular Basis of Mechanotransduction""; ""4.4 Chordotonal Organ""
505 8 _a""4.4.1 Fly Antenna and Johnstonâ#x80;#x99;s Organ""""4.4.2 Molecular Basis of Mechanotransduction""; ""4.5 Dendritic Arborization Neurons""; ""4.5.1 Overall Mechanics of da Neurons""; ""4.5.2 Molecular Basis of Mechanotransduction""; ""References""; ""Chapter 5: Drosophila Mechanotransduction Channels""; ""5.1 Overview""; ""5.2 No Mechanoreceptor Potential C (NompC)""; ""5.2.1 Overview on Fly NompC""; ""5.2.2 Structure of NompC""; ""5.2.3 Gating of NompC""; ""5.2.4 The Gating Spring of NompC""; ""5.2.5 NompC-Microtubule Interaction""; ""5.2.6 Physiological Roles of Fly NompC""
520 3 _aThis book offers an essential introduction for all graduate students and researchers who are working on or interested in mechanotransduction using fruit flies as their model organisms. Designed for accessibility, it follows a simple five-chapter structure, beginning with a general introduction to mechanotransduction in physiology (Chapter 1) and some basic considerations on the principles behind mechanotransduction processes (Chapter 2). In turn, Chapters 3, 4 and 5 focus on mechanoreceptors in Drosophila melanogaster. Chapter 3 explains how the fly's mechanosensitive cells (i.e. mechanoreceptors) contribute to its daily life, while Chapter 4 explores the ultrastructural and mechanical basis for the working mechanisms of various fly mechanoreceptors. Lastly, Chapter 5 elaborates on the structure, function and physiology of mechanosensitive molecules in fly mechanoreceptors. Accordingly, the book provides an overall framework, helping readers understand mechanosensory transduction, from the physiological level to the molecular level.
650 7 _aInsectos
_2embne
_0(OCoLC)fst00898408
_0
_9137904
700 1 _aLiu, Zhen.
700 1 _aSun, Landi.
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-981-10-6526-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017
998 _b02/2018
_dz
_e-
_zSI
999 _c96611
_d96611
_x1