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007			cr |n|||||||||
008			171004s2017 ja o 000 0 eng d
020			_a4431565698 _q(electronic bk.)
020			_a9784431565697 _q(electronic bk.)
020			_z4431565639
020			_z9784431565635
020			_z9784431565680
040			_aYDX _beng _cYDX _dN$T _dEBLCP _dGW5XE _dN$T _dNJR _dOTZ _dAZU _dUPM _dMERER _dOCLCF _dIOG _dCOO _dOCLCQ _dES-MaUEC _bspa
050		4	_aQP519.9.P48 _b2017 EB
245	0	0	_aPhotoaffinity labeling for structural probing within protein _cYasumaru Hatanaka, Makoto Hashimoto, editors.
264		1	_aTokyo _bSpringer International Publishing _c2017
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
500			_a _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505	0		_aPreface -- Chapter 1 Multifunctional Photoprobes for Identification of Ligand Sites within Biomolecules -- Chapter 2 Tag-Creation Approaches for Highly Efficient Profiling of Interacting Proteins and Domains -- Chapter 3 Recent Developments in Designing Compact Biological Photoprobes -- Chapter 4 Utilities of Anti-Ligand Antibody and Mass Spectrum to Elucidate Photolabelled Sites -- Chapter 5 Combination of Photoaffinity Label and Site-Directed Antibody for Target Proteins -- Chapter 6 Synthesis of diazirinyl photophore and optically pure diazirinylphenylalanines for photoaffinity labeling -- Chapter 7 Photoreactive biomacromolecules: preparation using photoreactive units and applications for analyzing biological interfaces -- Chapter 8 Covalently capturing protein interactions in living cells by site-specific incorporation of photo-cross-linkable amino acids -- Chapter 9 Use of hexose photolabels to reveal the structure and function of glucose transporters -- Chapter 10 The function of the mammalian peroxisome and analysis of the fatty acid oxidation system by photoaffinity labeling -- Chapter 11 Photoaffinity labeling methods to explore internalization mechanisms of arginine-rich cell-penetrating peptides -- Chapter 12 Photoaffinity Labeling in Drug Discovery Research.
520	3		_aThis book covers the most up-to-date photoaffinity labeling method to tackle the key loop module involved in the binding process of a bioactive small molecule to its host protein. The book introduces rational points for preparing powerful photoaffinity probes, keys for the efficient analysis of labeled products, and recent successful applications for protein probing. Regarding drug design, the unique topics of the book are the special consideration of the crosslinking potential of recent probes and their application of important receptor proteins . This book presents emerging technologies of photoaffinity labeling to readers who are working in the fields of proteomics, molecular recognition, and drug discovery and development.
650		7	_aFisiología animal _2embne _0(OCoLC)fst01061492 _0 _9140656
700	1		_aHashimoto, Makoto.
700	1		_aHatanaka, Yasumaru.
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-4-431-56569-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017
998			_b02/2018 _dz _e- _zSI
999			_c96559 _d96559 _x1