000			03294cam a2200409Ii 4500
001			96540
003			ES-MaUEC
005			20230102112759.0
006			m o d
007			cr cnu|||unuuu
008			170925s2017 sz a o 000 0 eng d
020			_a331960192X _q(electronic bk.)
020			_a9783319601922 _q(electronic bk.)
020			_z3319601911
020			_z9783319601915 _q(print)
040			_aGW5XE _beng _erda _epn _cGW5XE _dYDX _dNJR _dAZU _dUPM _dMERER _dOCLCF _dOCLCO _dUAB _dIOG _dCOO _dOCLCO _dOCLCQ _dJG0 _dOCLCO _dOCLCA _dES-MaUEC _bspa
050		4	_aQP356.22 _b2017 EB
245	0	0	_aGenome editing in neurosciences _cRudolf Jaenisch, Feng Zhang, Fred Gage, editors.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2017
300			_a1 recurso en línea (xi, 123 páginas) _bilustraciones (algunas a color)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aResearch and perspectives in neurosciences _x0945-6082
500			_a _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505	0		_aIntroduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington's Disease -- Therapeutic gene editing in muscles and muscle stem cells.
506	0		_aOpen access. _5GW5XE
520	3		_aThis book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
650		7	_aGenetic engineering. _2fast _0(OCoLC)fst00940027 _0
700	1		_aGage, F. _q(Fred), _d1950- _eeditor literario
700	1		_aJaenisch, Rudolf, _eeditor literario
700	1		_aZhang, Feng _c(Professor of plant biology) _d1982- _eeditor literario _993501
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-60192-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017
998			_b02/2018 _dz _e- _zSI
999			_c96540 _d96540 _x1