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020 _a3319592424
020 _a9783319592428
020 _z3319592408
020 _z9783319592404
040 _aEBLCP
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050 4 _aRC254.5
_b2017 EB
100 1 _aWang, Yuzhuo.
_eautor
245 1 0 _aTumor Dormancy and Recurrence.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (85 páginas)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
490 0 _aCancer Drug Discovery and Development
504 _aIncluye referencias bibliográficas
505 0 _aPreface; Contents; Epigenetic Regulation of Cancer Dormancy as a Plasticity Mechanism for Metastasis Initiation; Introduction; Cancer Cell Dormancy within the Dogma of Metastasis; Defining Dormancy States; Microenvironmental Signals Regulate Dormancy; Epigenetic Regulation of Dormancy Transcriptional Programs; Transcriptional Programs in Adult Stem Cells and Dormant Cancer Cells; Transcriptional Programs in Dormant Residual Disease in Patients; Conclusions; References; Biological and Clinical Evidence for Metabolic Dormancy in Solid Tumors Post Therapy; Introduction.
505 8 _aMetronomic Chemotherapy and the Anti/pro-Angiogenic Growth Factor Equilibrium Metronomic Chemotherapy and the Circulating Endothelial Progenitors; Conclusions; References; Immuno-oncology of Dormant Tumours; Anti-cancer Immunity: An Overview; Dormant Tumour-Immune System Interactions; Immunotherapy for Dormant Tumours; References; Thermodynamics and Cancer Dormancy: A Perspective; Introduction: Entropy and Information; Complexity of Cancer; Molecular Scale; Cellular Scale; Tissue Scale; Metabolic Entropy Increase in Cancer; Organismal Scale; Epidemiological Scale; Conclusions.
505 8 _aThe Derangement of Metabolic Wiring in Cancer 'Metabolic' Dormancy and Related Biological Mechanisms; Regulation of Metabolic Dormancy; Technological, Biological, and Clinical Challenges to Study Metabolic Tumor Dormancy; Premise of Therapeutic Targeting of Metabolic Dormancy; Conclusions; References; Tumor Dormancy, Angiogenesis and Metronomic Chemotherapy; Introduction; The Role of Angiogenesis in Tumor Dormancy; Metronomic Chemotherapy as an Inducer of Angiogenic Tumor Dormancy: A Promising Research Field.
520 3 _aThis volume will be the first to provide a comprehensive description of tumor dormancy. It will define the clinical and biological aspects of this phenomenon, as well as the cellular and molecular mechanisms associated with tumor dormancy. Chapters will be authored by world-renewed experts who are conducting cutting-edge research in the field. A unique feature will be a conclusive paragraph detailing future development and foreseeable clinical applications at the end of each chapter. The volume will serve as a fundamental instrument for every researcher and clinician interested in the field of tumor dormancy as well as a means of disseminating stimulating concepts and prompting the development of innovative technological solutions.
650 7 _9139209
_aTumores
_xGrowth.
_2fast
_0(OCoLC)fst01158769
_0
700 1 _aCrea, Francesco.
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-59242-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988 _aSpringer_Medicine_2017
998 _b02/2018
_dz
_e-
_zSI
999 _c96500
_d96500
_x1