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008			170906s2017 sz a ob 000 0 eng d
020			_a3319520733 _q(electronic bk.)
020			_a9783319520735 _q(electronic bk.)
020			_z3319520717
020			_z9783319520711
040			_aYDX _beng _cYDX _dN$T _dEBLCP _dGW5XE _dDKU _dN$T _dUAB _dAZU _dUPM _dOCLCF _dMERER _dOCLCQ _dESU _dYDX _dIOG _dCOO _dOCLCO _dOCLCQ _dJG0 _dOCLCO _dOCLCA _dOHI _dES-MaUEC _bspa
050		4	_aQP461 _b2017 EB
245	0	0	_aUnderstanding the cochlea _cGeoffrey A. Manley, Anthony W. Gummer, Arthur N. Popper, Richard R. Fay, editors.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2017
300			_a1 recurso en línea _bilustraciones
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aSpringer handbook of auditory research _vv. 62
500			_a _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505	0		_aAcoustical Society of America; Series Preface; Preface 1992; Volume Preface; Contents; Contributors; 1 Major Advances in Cochlear Research; Abstract; 1.1 Introduction; 1.2 The Cochlea: What It Is, Where It Came From, and What Is Special About It; 1.3 New Directions in Cochlear Development; 1.4 Mechanical Transduction Processes in the Hair Cell; 1.5 Prestin: Molecular Mechanisms Underlying Outer Hair Cell Electromotility; 1.6 Electromechanical Feedback Mechanisms and Power Transfer in the Mammalian Cochlea; 1.7 Hair Cells and Their Synapses
505	8		_a1.8 Afferent Coding and Efferent Control in the Normal and Impaired Cochlea; 1.9 Ion and Fluid Homeostasis in the Cochlea; 1.10 Remote Sensing the Cochlea: Otoacoustics; 1.11 Localized Internal Stimulation of the Living Cochlea Using Electrical and Optical Methods; 1.12 Summary and Outlook; Compliance with Ethics Requirements; References; 2 The Cochlea: What It Is, Where It Came From, and What Is Special About It; Abstract; 2.1 Introduction; 2.2 Where Did the Cochlea Come From?; 2.3 What Is Special About the Cochlea?; 2.3.1 The Loss of the Lagena; 2.3.2 The Advent of Bony Laminae
505	8		_a2.3.3 Modifications of the Prestin Molecule; 2.4 Did Coiling Have Any Effect on Function?; 2.5 The Cochlea (Also) Determines the Hearing Range; 2.6 Variation in Cochlear Form and Dimensions; 2.7 Cochleae and Other Hearing Organs; 2.8 Summary; Compliance with Ethics Requirements; References; 3 New Directions in Cochlear Development; Abstract; 3.1 Introduction; 3.2 Embryonic Origin of the Mammalian Cochlea; 3.2.1 Defining the Cardinal Axes of the Inner Ear; 3.2.2 Transforming the Ventral Otocyst into the Cochlear Duct; 3.2.3 Outstanding Issues Concerning the Embryonic Origin of the Cochlea
505	8		_a3.3 Formation of the Cochlear Prosensory Domain; 3.3.1 Role of Notch Signaling and Sox2 in the Formation of Prosensory Patches; 3.3.2 Role of Other Signaling Pathways in the Induction of the Cochlear Prosensory Domain: Fibroblast Growth Factors, Bone Morphogenetic Proteins, and Wnts; 3.3.3 Outstanding Issues Concerning the Induction and Radial Patterning of the Prosensory Domain; 3.4 Coordinating Developmental Gradients of Differentiation and Cell Cycle Exit in the Cochlea; 3.4.1 The Unusual Pattern of Cell Cycle Exit and Differentiation in the Cochlea
505	8		_a3.4.2 How Are Cell Cycle Exit and Differentiation Uncoupled in the Cochlea?; 3.4.3 Outstanding Issues Concerning Cell Cycle Exit and Differentiation in the Prosensory Domain; 3.5 Fine-Grained Patterning and Cell-Type Specification in the Organ of Corti; 3.5.1 Notch Signaling as a Mechanism to Distinguish Hair Cells from Supporting Cells; 3.5.2 Specification of Subtypes of Hair Cells and Supporting Cells in the Organ of Corti; 3.5.3 Outstanding Issues Concerning the Specification of Hair Cell and Supporting Cell Subtypes; 3.6 Innervation of the Organ of Corti
520	3		_aThis SHAR volume serves to expand, supplement, and update the original "Cochlea" volume in the series. The book aims to highlight the power of diverse modern approaches in cochlear research by focusing on advances in those fields over the last two decades. It also provides insights into where cochlear research is going, including new hearing prostheses for the deaf that will most likely soon enter the phase of clinical trials. The book will appeal to a broad, interdisciplinary readership, including neuroscientists and clinicians in addition to the more specific auditory community.
650		7	_aCóclea _2embne _0(OCoLC)fst00866070 _0 _9672829
700	1		_aFay, Richard R. _984151
700	1		_aGummer, A. W. _q(Anthony W.)
700	1		_aManley, Geoffrey A., _d1945- _984934
700	1		_aPopper, Arthur N. _984152
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-52073-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017
998			_b02/2018 _dz _e- _zSI
999			_c96483 _d96483 _x1