000			05067cam a2200409Ii 4500
001			96474
003			ES-MaUEC
005			20230102112755.0
006			m o d
007			cr |||||||||||
008			170905t20172017sz a ob 000 0 eng d
020			_a4431565507 _q(electronic bk.)
020			_a9784431565505 _q(electronic bk.)
020			_z4431565485 _q(hardcover ; _qalk. paper)
020			_z9784431565482 _q(hardcover ; _qalk. paper)
040			_aMMU _beng _erda _epn _cMMU _dGW5XE _dYDX _dN$T _dOCLCQ _dN$T _dOCLCF _dCASUM _dTFH _dMERER _dIOG _dCOO _dOCLCO _dOCLCQ _dOH1 _dJG0 _dOCLCO _dOCLCA _dUAB _dES-MaUEC _bspa
050		4	_aQP624.75.P74 _b2017 EB
245	0	0	_aDrebrin : _bfrom structure and function to physiological and pathological roles _cTomoaki Shirao, Yuko Sekino, editors.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2017
264		4	_c2017
300			_a1 recurso en línea (xii, 345 páginas) _bilustraciones (algunas a color)
336			_astill image _bsti _2rdacontent
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in experimental medicine and biology _x2214-8019 _vvolume 1006
500			_a _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
504			_aIncluye referencias bibliográficas
505	0		_aHistory of drebrin discovery as an general introduction. General introduction to drebrin / Tomoaki Shirao, Yuko Sekino -- Basic information about drebrin. Molecular cloning of drebrin: progress and perspectives / Nobuhiko Kojima -- Biochemistry of drebrin and its binding to actin filaments / Ryoki Ishikawa -- Phosphorylation of drebrin and its role in neuritogenesis / Phillip R. Gordon-Weeks -- Remodeling of actin filaments by drebrin a and its implications / Elena E. Grintsevich -- Cell shape change by drebrin / Kensuke Hayashi -- Drebrin in nervous system. Localization of drebrin: light microscopy study / Tomoaki Shirao, Noriko Koganezawa, Hiroyuki Yamazaki, Kenji Hanamura, Kazuyuki Imamura -- Making of a synapse: recurrent roles of drebrin a at excitatory synapses throughout life / Chiye Aoki, Ang D. Sherpa -- Drebrin in neuronal migration and axonal growth / Kenji Hanamura -- Drebrin and spine formation / Hideto Takahashi, Yusuke Naito -- Role of drebrin in synaptic plasticity / Yuko Sekino, Noriko Koganezawa, Toshiyuki Mizui, Tomoaki Shirao -- Drebrin in Alzheimer's disease / Yuta Ishizuka, Kenji Hanamura -- Drebrins and connexins: a biomedical perspective / Irina V. Majoul, Justus S. Ernesti, Eugenia V. Butkevich, Rainer Duden -- Homer, spikar, and other drebrin-binding proteins in the brain / Hiroyuki Yamazaki, Tomoaki -- Role of drebrin at the immunological synapse / Vera Rocha-Perugini, Mónica Gordon-Alonso, Francisco Sánchez-Madrid -- Drebrin regulation of calcium signaling in immune cells / Jonathan Pabon, Man Kit Law, Avery August -- Drebrin and spermatogenesis / Haiqi Chen, Michelle W.M. Li, C. Yan Cheng -- Drebrin at junctional plaques / Wiebke K. Ludwig-Peitsch -- Juxtanuclear drebrin-enriched zone / Wiebke K. Ludwig-Peitsch -- Drebrin in renal glomeruli / Wiebke K. Ludwig-Peitsch.
520	3		_aThis book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer's disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines"--Publisher's description.
650		7	_aADN _2embne _0(OCoLC)fst00886613 _0 _9140806
700	1		_aSekino, Yuko, _eeditor literario
700	1		_aShirao, Tomoaki, _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-4-431-56550-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017
998			_b02/2018 _dz _e- _zSI
999			_c96474 _d96474 _x1