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008			170905t20172017sz a ob 000 0 eng d
020			_a3319624148 _q(electronic bk.)
020			_a9783319624143 _q(electronic bk.)
020			_z3319624121 _q(hardcover : alk. paper)
020			_z9783319624129 _q(hardcover : alk. paper)
040			_aMMU _beng _erda _cMMU _dEBLCP _dGW5XE _dOCLCF _dTFH _dYDX _dN$T _dAZU _dUPM _dMERER _dCASUM _dIOG _dCOO _dOCLCO _dOCLCQ _dOCLCO _dJG0 _dOCLCO _dOCLCA _dES-MaUEC _bspa
050		4	_aQH485 _b2017 EB
245	0	0	_aPericonception in physiology and medicine _cAlireza Fazeli, William V. Holt, editors.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2017
264		4	_c2017
300			_a1 recurso en línea (x, 179 páginas) _bilustraciones (algunas a color)
336			_astill image _bsti _2rdacontent
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aAdvances in experimental medicine and biology _x2214-8019 _vvolume 1014
500			_a
504			_aIncluye referencias bibliográficas
505	0		_aIntroduction: a brief guide to the periconception environment / Alireza Fazeli, William V. Holt -- Epigenetic influences during the periconception period and assisted reproduction / Akwasi A. Amoako, Tamer M. Nafee [and others] -- The importance of the periconception period: immediate effects in cattle breeding and in assisted reproduction such as artificial insemination and embryo transfer / Mieke Van Eetvelde, Sonia Heras, J. L. M. R. Leroy, Ann Van Soom, Geert Opsomer -- The consequences of maternal-embryonic cross talk during the periconception period on subsequent embryonic development / Dimitrios Rizos, Veronica Maillo, Maria-Jesús Sá́nchez-Calabuig [and others] -- The role of maternal nutrition during the periconceptional period and its effect on offspring phenotype / Tom P. Fleming, Judith J. Eckert, Oleg Denisenko -- The long-term effect of the periconception period on the embryo's epigenetic profile and phenotype: the role of maternal disease such as diabetes and how the effect is mediated (example from a rabbit model) / Bernd Fischer, Maria Schindler, S. Mareike Pendzialek, Jacqueline Gürke, Elisa Haucke [and others] -- Long-term effects of the periconception period on embryo epigenetic profile and phenotype: the role of stress and how this effect is mediated / James Ord, Alireza Fazeli, Penelope J. Watt -- The long-term effects of the periconceptional period on embryo epigenetic profile and phenotype; the paternal role and his contribution, and how males can affect offspring's phenotype/epigenetic profile / Emma S. Lucas, Adam J. Watkins -- Exploitation of non-mammalian model organisms in epigenetic research / William V. Holt.
520	3		_a"This book presents a timely collection of reviews by experts in periconception and fertilization. The book provides a good introduction for those new to the field as well as those who have worked in this field for some time, but not have been able to keep up-to-date with recent advances on the topic. The book reviews the current knowledge in this field, then focuses its attention on short-term and long-term effects of the periconception period, both from a physiological and medical perspective. Finally the volume covers the examination of the potential mechanisms involved in controlling periconception period. From the early days of discovery about the basics of the fertilization process, scientist shave known that early events happening during conception play a major part in the creation of new offspring. However, until nearly a decade ago we thought these events were just concerned with the conception and nothing to do with lifelong health and welfare, or wellbeing of the offspring. Early indications from IVF in sheep and cattle suggested that the embryo culture conditions employed in the laboratory could result in unusually large and unhealthy offspring. These observations sounded alarm bells and stimulated research into the impacts of in vivo and in vitro conditions on the health of embryos and offspring. This book provides a summary of the state-of-the-art research being done to more fully understand the importance of the periconception environment"--Publisher's description.
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017
650		7	_aFecundación _2embne _9677526
700	1		_aAlireza, Fazeli, _eeditor literario
700	1		_aHolt, William V., _eeditor literario _985023
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-62414-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI