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008			170901s2017 xx o 000 0 eng d
020			_a3319618040 _q(electronic bk.)
020			_a9783319618043 _q(electronic bk.)
020			_z3319618032
020			_z9783319618036
040			_aYDX _beng _cYDX _dN$T _dEBLCP _dN$T _dGW5XE _dUAB _dAZU _dUPM _dOCLCF _dMERER _dOCLCQ _dESU _dIOG _dCOO _dES-MaUEC _bspa
050		4	_aQR357 _b2017 EB
245	0	0	_aViruses, genes, and cancer _cEric Hunter, Klaus Bister, editors.
264		1	_a[S.l.] _bSpringer International Publishing _c2017
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aCurrent topics in microbiology and immunology _vv. 104
500			_a _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505	0		_aPreface; A Brief Homage to Peter Vogt; Contents; 21 Exchange of Genetic Sequences Between Viruses and Hosts; Abstract; 1 A Year of Virological Anniversaries; 1.1 Bacteriophage and Prokaryote Transduction; 1.2 The Debt of Tumor Virus Research to Phage Genetics; 1.3 Fifty-Five Years of Peter Vogt's Contributions to Retroviruses and Oncogenes; 2 Acquisition of Host Genes by Viruses; 2.1 Oncogenesis by Simple Retroviruses and Transduction of Oncogenes; 2.2 Why Is Retroviral Transduction not a Major Driver of Virus or Host Evolution?
505	8		_a2.3 Incorporation of Host Genetic Sequences into Complex Viruses3 Acquisition of Viral Genes by Hosts; 3.1 Viral Genomes in Host DNA: Retroviruses, DNA Viruses and RNA Viruses; 3.2 Evolutionary Dynamics of Exogenous and Endogenous Retroviruses; 3.3 Pathogenic and Beneficial Attributes of Endogenous Retroviruses; 3.4 Role of Endogenous Retroviral Envelopes in the Placenta; 4 Endosymbiont Organelles in Eukaryotic Cells and Their Horizontal Transfer in Cancer; 4.1 Evolution of Complex Cells and Their Organelles; 4.2 Horizontal Spread of Cancer Cells
505	8		_a3 Infectious Agents in Bovine Red Meat and Milk and Their Potential Role in Cancer and Other Chronic DiseasesAbstract; 1 Increased Cancer Risk After Red Meat or Dairy Product Consumption; 2 Risk Reduction for Specific Cancers and Two Chronic Diseases by Long-Time Breast-Feeding; 3 Are Diet-Attributed Factors Increasing Cancer Risks Human-Specific?; 4 Increased Risk for Neurodegenerative Diseases After Red Meat or Dairy Product Consumption; 5 Increased Risk for Cardiovascular or Autoimmune Diseases After Red Meat or Dairy Product Consumption
505	8		_a4.3 Colonization of Cancer Cells by Host Mitochondria5 Concluding Remarks; Acknowledgements; References; 33 Virus-Host Gene Interactions Define HIV-1 Disease Progression; Abstract; 1 Introduction; 2 HIV-1 Transmission; 3 Current Concepts of Genital Tract Infection and Systemic Spread; 4 HIV-1 Transmission is Linked to a Genetic Bottleneck; 5 Evidence for Both Chance and Selection Influencing Transmission; 6 Properties of the Transmitted/Founder Virus; 7 A Complex Interplay Between Host Immunity and Transmitted Virus Phenotype Defines Viral Control and Disease Progression; 8 Conclusions
520	3		_aThis volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes - such as oncogenes, proto-oncogenes, or tumor suppressor genes - in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.
650		7	_aCancer _xEtiology. _2fast _0(OCoLC)fst00845361 _9139308 _0comprobar BNE19900970859
700	1		_aBister, Klaus.
700	1		_aHunter, Eric.
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-61804-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017
998			_b02/2018 _dz _e- _zSI
999			_c96468 _d96468 _x1