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020 _a3319607332
_q(electronic bk.)
020 _a9783319607337
_q(electronic bk.)
020 _z3319607316
_q(hardcover : alk. paper)
020 _z9783319607313
_q(hardcover : alk. paper)
040 _aMMU
_beng
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066 _c(S
050 4 _aRM30.3.G45
_b2017 EB
245 0 0 _aPersonalised medicine :
_blessons from neurodegeneration to cancer
_cSherif El-Khamisy, editor.
246 3 _aPersonalized medicine :
_blessons from neurodegeneration to cancer
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2017
264 4 _c2017
300 _a1 recurso en línea (viii, 260 páginas)
_bilustraciones (algunas a color)
336 _astill image
_bsti
_2rdacontent
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
490 0 _aAdvances in experimental medicine and biology
_x2214-8019
_vvolume 1007
500 _a
_bSpringer Biomedical and Life Sciences eBooks 2017 English+International
504 _aIncluye referencias bibliográficas
505 0 _aApproaches for identifying novel targets in precision medicine: lessons from DNA repair / Dean T. Williams, Christopher J. Staples -- Nucleotide excision repair: from neurodegeneration to cancer / Anastasios Liakos, Matthieu D. Lavigne, Maria Fousteri -- Role of protein linked DNA breaks in cancer / Walaa R. Allam, Mohamed E. Ashour, Amr A. Waly, Sherif El-Khamisy -- The emerging role of proteomics in precision medicine: applications in neurodegenerative diseases and neurotrauma / Rana Alaaeddine, Mira Fayad, Eliana Nehme, Hisham F. Bahmad, Firas Kobeissy -- The role of nitric oxide from neurological disease to cancer / Ahmed Maher, Mohamed F. Abdel Rahman, Mohamed Z. Gad -- RNA nuclear export: from neurological disorders to cancer / Guillaume M. Hautbergue -- Can astrocytes be a target for precision medicine? / Chloe F. Allen, Pamela J. Shaw, Laura Ferraiuolo -- Mitochondrial diseases as model of neurodegeneration / Laila A. Selim, Heba Hassaan -- Personalised medicine: genome maintenance lessons learned from studies in yeast as a model organism / Arwa A. Abugable, Dahlia A. Awwad, Dalia Fleifel, Mohamed M. Ali, Sherif El-Khamisy [and others] -- The power of zebrafish in personalised medicine / Sarah Baxendale, Freek van Eeden, Robert Wilkinson -- Personalized medicine and resurrected hopes for the management of Alzheimer's disease: a modular approach based on GSK-3[beta] inhibitors / Reem K. Arafa, Nehal H. Elghazawy -- Regenerative medicine: advances from developmental to degenerative diseases / Nicholas F. Blair, Thomas J. R. Frith, Ivana Barbaric -- Gene therapy in the nervous system: failures and successes / Jayanth S. Chandran, Joseph M. Scarrott, Pamela J. Shaw, Mimoun Azzouz.
520 3 _a"The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease. The past 20 years has witnessed extensive research and progress in this area and scientists started to design new therapies harnessing individual genetic differences among patients to combatdegenerative disorders and cancer. We summarize these advancements and discuss perspectives for the future of personalized medicine"--Publisher's description.
650 7 _aFarmacología
_2embne
_0(OCoLC)fst01910010
_0
_9137893
700 1 _aEl-Khamisy, Sherif,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-60733-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
880 0 _6505-00
_aPreface - Personalised Medicine: Lessons from Neurodegenration to Cancer, Sherif F. El-Khamisy -- chap. 1 Approaches for Identifying Novel Targets in Precision Medicine: Lessons from DNA Repair, Dean T. Williams et al -- chap. 2 Nucleotide excision repair: from neurodegeneration to cancer, Liakos et al -- chap. 3 The Role of Protein-Linked DNA Breaks in Personalized Medicine Walaa R. et al -- chap. 4 The Emerging Role of Proteomics in Precision Medicine: Application in Neurodegenerative Diseases and Neurotrauma, Rana Alaaeddine et al -- chap. 5 The Role of Nitric Oxide from Neurological Disease to Cancer, Ahmed Maher et al -- chap. 6 RNA nuclear export: from neurological disorders to cancer, Guillaume M. Hautbergue -- chap. 7. Can astrocytes be a target for precision medicine, Chloe Allen et al -- chap. 8 Mitochondrial Diseases as Model of Neurodegeneration, Laila A. Selim et al -- chap. 9 Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism, Arwa A. Abugable et al -- chap. 10 The Power of Zebrafish in Personalised Medicine, Sarah Baxendale et al -- chap. 11 Alzheimer's Disease: a Modular Approach Based on GSK-3β Inhibitors Reem k. Arafa et al -- chap. 12. Regenerative medicine: advances from developmental to degenerative diseases, Nicholas F. Blair et al -- chap. 13 Gene therapy in the nervous system: failures and successes, Jayanth S. Chandran et al -- index.
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017
998 _b02/2018
_dz
_e-
_zSI
999 _c96453
_d96453
_x1