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008			170819s2017 si o 000 0 eng d
020			_a9789811052033 _q(electronic bk.)
020			_a9811052034 _q(electronic bk.)
020			_z9789811052026
020			_z9811052026
040			_aEBLCP _beng _epn _cEBLCP _dOCLCO _dN$T _dGW5XE _dYDX _dDKU _dOCLCF _dUAB _dAZU _dUPM _dMERER _dOCLCQ _dESU _dCASUM _dIOG _dCOO _dOCLCQ _dOCLCO _dJG0 _dOCLCO _dOCLCQ _dOCLCA _dES-MaUEC _bspa
050		4	_aQP623 _b2017 EB
245	0	0	_aLong non coding RNA biology _cM.R.S. Rao, editor.
264		1	_aSingapore _bSpringer International Publishing _c2017
300			_a1 recurso en línea (336 páginas)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _vv. 1008
500			_a3.2 Regulatory lncRNAs Affecting Enhancer/Promoter Activities and Chromatin Organization.
500			_a _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505	0		_aForeword; Preface; Contents; About the Editor; Chapter 1: History, Discovery, and Classification of lncRNAs; 1.1 A Hundred-Years History of RNA Biology; 1.1.1 From "Nuclein" to Nucleic Acids and to the Double Helix; 1.1.2 A Central Role for RNA in Cell Biology: The RNA World Concept; 1.1.3 Bacterial sRNAs: Pioneers of Regulatory ncRNAs; 1.1.4 MicroRNAs and RNA Interference; 1.2 LncRNA Discovery in the Pre-genomic Era; 1.2.1 H19: The Very First Eukaryote lncRNA Gene; 1.2.2 X Inactivation: Existence of Xist; 1.3 From Non-coding Genome to Non-coding Transcriptome: The Genomic Era.
505	8		_a1.3.1 The Human Genome Project: Genomic DNA Is Mostly Non-coding1.3.2 Pervasive Transcription and the Dark Matter of the Genome; 1.4 Non-coding RNAs: Junk or Functional; 1.4.1 Origin of lncRNA Genes; 1.4.2 Evolutionary Conservation of lncRNAs; 1.4.3 Role of lncRNAs in Biological Diversity; 1.5 The General Portrait of lncRNA Genes and Transcripts; 1.5.1 Coding Potential of lncRNA Genes; 1.5.2 LncRNA Transcription and Transcript Organization; 1.5.3 Chromatin Signatures of lncRNAs Genes; 1.5.4 Expression Pattern of lncRNAs: Stability, Specificity, and Abundance.
505	8		_a1.5.5 Subcellular Localization of lncRNAs1.5.6 Structure of lncRNAs; 1.6 Classification of lncRNAs; 1.6.1 Classification According to lncRNA Length; 1.6.2 Classification According to lncRNA Location with Respect to PCGs; 1.6.3 Classification According to lncRNA Residence Within Specific DNA Regulatory Elements and Loci; 1.6.4 Classification According to lncRNA Biogenesis Pathways; 1.6.5 Classification According to lncRNA Subcellular Localization or Origin; 1.6.6 Classification According to lncRNA Function; 1.6.7 Classification According to lncRNA Association with Specific Biological Processes.
505	8		_a1.6.8 Future Challenges in lncRNA Annotation and ClassificationReferences; Chapter 2: Long Noncoding RNA: Genome Organization and Mechanism of Action; 2.1 Introduction; 2.2 lncRNA and Chromatin Regulation; 2.3 lncRNAs Regulate Chromatin Structure via Histone Modifications; 2.4 lncRNAs Regulate Chromatin Remodeling; 2.5 eRNAs and Higher-Order Chromatin Organization; 2.6 Long Noncoding RNAs in Genomic Imprinting; 2.7 Posttranscriptional Regulation by lncRNAs; 2.8 lncRNAs in Staufen-Mediated mRNA Decay; 2.9 Biology of Natural Antisense Transcripts.
505	8		_a2.10 lncRNA-Mediated Regulation of Protein Activity2.11 Nuclear Architecture and Long Noncoding RNAs; 2.12 lncRNAs and Nucleolar Function; 2.13 lncRNAs Are Critical Components of Paraspeckles; 2.14 lncRNAs in Nuclear Speckles and Polycomb Bodies; 2.15 lncRNA and Topological Organization of Multichromosomal Regions; 2.16 lncRNAs and Centromere Function; 2.17 Conclusion and Outlook; References; Chapter 3: From Heterochromatin to Long Noncoding RNAs in Drosophila: Expanding the Arena of Gene Function and Regulation; 3.1 Introduction.
520	3		_aThis contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.
650		7	_aARN _2embne _0(OCoLC)fst01741020 _0 _9144940
700	1		_aRao, M. R. S.
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-981-10-5203-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017
998			_b02/2018 _dz _e- _zSI
999			_c96439 _d96439 _x1