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001			96408
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006			m o d
007			cr |n|---aucuu
008			170812s2017 sz o 000 0 eng d
020			_a3319480545 _q(electronic bk.)
020			_a9783319480541 _q(electronic bk.)
020			_z3319480537
020			_z9783319480534
040			_aEBLCP _cEBLCP _dGW5XE _dN$T _dYDX _dDKU _dOCLCF _dUAB _dAZU _dOCLCQ _dUPM _dOCLCQ _dMERER _dOCLCQ _dESU _dIOG _dCOO _dES-MaUEC _bspa
050		4	_aRC280.B6 _b2017 EB
245	0	0	_aDevelopment of oral cancer : _brisk factors and prevention strategies _cAla-Eddin Al Moustafa, editor.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2017
300			_a1 recurso en línea (219 páginas)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
505	0		_aPreface; Contents; 1: Human Oral Cancer (Epidemiology and Characteristic); 1.1 Introduction; 1.2 Oral Cancer Epidemiology; 1.2.1 Incidence and Mortality; 1.2.2 Age and Gender; 1.2.3 Site; 1.2.4 Trends and Variations; 1.2.5 2035 Projection; 1.2.6 Survival; 1.3 Clinical Characteristics; 1.4 Early Detection and Prevention of Oral Cancer; 1.4.1 Primary Prevention; 1.4.2 Secondary Prevention (Screening); References; 2: Novel Developments in the Molecular Genetic Basis of Oral Squamous Cell Carcinoma (OSCC); 2.1 Introduction; 2.2 Transcriptional Factors.
505	8		_a2.3 Tumor Suppressor Genes or Anti-oncogenes2.4 Proto-oncogenes and Oncogenes; 2.5 Gene Expression; 2.6 Cell Surface Receptors; 2.7 Epigenetic Changes; 2.8 Chromosomal Instability and Copy Number Variation; 2.9 mtDNA Mutation; 2.10 Telomeres and Telomerase; 2.11 Microsatellite Instability and Alteration; 2.12 Noncoding RNA; 2.13 MicroRNA (miRNA); 2.14 Long Noncoding RNAs (lncRNAs); References; 3: Oral Cancer: After the Completion of the Human Genome Project; 3.1 Gene Profiling: (A Personal Journey); 3.2 Drug Design to Shut Off Bad Genes; References; 4: Smoking and Oral Cancer.
505	8		_a4.1 Introduction4.2 History of Tobacco Usage; 4.3 Cigarettes and Other Forms of Tobacco Preparations; 4.4 Composition and Carcinogenesis; 4.5 Effects on Oral Health; 4.5.1 Oral Hygiene and Aesthetics; 4.5.2 Oral Mucosal Diseases: Nonmalignant; 4.5.3 Oral Premalignant Disorders; 4.5.4 Oral Cancer; 4.6 Prevention Strategies; References; 5: Alcohol and Oral Cancer; 5.1 Introduction; 5.2 Alcohol and Oral Cancer: Epidemiological Evidence; 5.3 Alcoholic Beverages and Weekly Consumption; 5.4 Topical Effects; 5.5 Systemic Effects; 5.6 Synergistic Effects with Tobacco Use.
505	8		_a5.7 Alcohol-Related Oral Carcinogenesis5.8 Alcohol-Containing Mouthwashes and Oral Cancer; 5.9 Prevention; References; 6: High-Risk Human Papillomaviruses and Epstein-Barr Virus Presence and Crosstalk in Human Oral Carcinogenesis; 6.1 Introduction; 6.2 High-Risk Human Papillomaviruses (HPVs) in Human Cancer; 6.3 Epstein-Barr Virus (EBV) in Human Cancer; 6.4 High Risk of HPVs and EBV in Human Oral Cancer; 6.5 Conclusion and Perspectives; References; 7: Oral Cancer: Epidemiology and Infections (Bacterial and Fungal) Global Incidence; 7.1 Introduction.
505	8		_a7.2 Worldwide Incidence of Oral Cancer by Gender, Age and Primary Site7.3 Oral Cancer Mortality and Survival; 7.4 Bacteria and Cancer; 7.4.1 Anatomy; 7.4.2 Clinical Presentation; 7.4.3 Pathology; 7.4.4 Virus; 7.4.4.1 HPV; 7.4.4.2 Human Immunodeficiency Virus; 7.4.4.3 Herpes Simplex Virus; 7.4.5 Dental Considerations; 7.4.5.1 Hygiene; 7.4.5.2 Dentures; 7.4.5.3 Oral Cancer in the UAE; References; 8: Oral Cancer and Chewing Habits; 8.1 Introduction; 8.2 Oral Cancer Statistics: Global Incidence, Prevalence, Mortality, and Survival.
520	3		_aThis book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. Some of the discussed risk factors are well known, including smoking, alcohol, betel quid chewing, and oncoviruses such as high-risk human papillomaviruses and Epstein-Barr virus; however, careful attention is also paid to less widely recognized factors, such as Qat chewing and yerba Mate consumption. The book concludes by describing and evaluating the most important strategies currently available for the prevention of oral carcinogenesis in humans. In presenting the most up-todate research and knowledge on these topics, this book will serve as a valuable source of up-to-date information for oncologists, cancer scientists, and medical students.
650		7	_aBoca _xCancer _xEtiology. _2embne _0(OCoLC)fst01028435 _0 _9139120
700	1		_aAl Moustafa, Ala-Eddin.
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-48054-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aSpringer_Medicine_2017
998			_b02/2018 _dz _e- _zSI
999			_c96408 _d96408 _x1