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001			96342
003			ES-MaUEC
005			20230102112750.0
006			m o d
007			cr cnu|||unuuu
008			170718s2017 sz a o 001 0 eng d
020			_a3319554468
020			_a3319554484 _q(electronic bk.)
020			_a9783319554464
020			_a9783319554488 _q(electronic bk.)
020			_z9783319554464 _q(print)
040			_aN$T _cN$T _dGW5XE _dN$T _dYDX _dOCLCF _dNJR _dUAB _dESU _dAZU _dUPM _dIOG _dCOO _dOCLCQ _dMERER _dVT2 _dOCLCQ _dOCLCO _dJG0 _dOCLCO _dOCLCA _dES-MaUEC _bspa
050		4	_aRC268.6 _b2017 EB
245	0	0	_aEssential and non-essential metals : _bcarcinogenesis, prevention and cancer therapeutics _cAnuradha Mudipalli, Judith T. Zelikoff, editors.
264		1	_aCham, Switzerland _bHumana Press _c2017.
300			_a1 recurso en línea (xii, 228 páginas) _bilustraciones (algunas a color)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aMolecular and integrative toxicology _x2168-4219
500			_aIncluye índice
500			_aSpringerLink _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505	0		_aCalcium channels and pumps important during lactation as potential targets for breast cancer -- Tumor development through the Mg2+nifying glass -- Selenium: roles in cancer prevention and therapies -- Zinc and Zinc-Dependent Proteins in Cancer adn Chemotherapeutics -- Arsenic Carcinogenesis -- Cadmium Carcinogenesis and Mechanistic Insights -- Molecular Mechanisms of Chromium-Induced Carcinogenesis -- Mechanisms of Nickel Carcinogenesis -- Application of Metallomics and Metalloproteomics for Understanding the Molecular Mechanisms of Action of Metal-based Drugs.
520	3		_aThis book aims to present current state of understanding of the role of metals in human health and disease. As it will be difficult to cover all of the metals, about two scores of them, the authors will instead provide a detailed analysis of a select set of essential (Calcium, Magnesium, Selenium, Iron, copper and Zinc) and non-essential metals (Nickel, Chromium, Cadmium and Arsenic, Tungsten and Asbestos). Each chapter will have a dedicated section focusing on the binary role that some of these metals play, their carcinogenic and cancer therapeutics, by integrating epidemiological, experimental evidence with special emphasis and focus on molecular mechanisms involved in these processes. The biological analysis will also include emerging lines of evidence such as micro RNAS, kinase families, receptors, endoplasmic, mitochondrial players and epigenetics. As part of integrating the human, experimental and mechanistic data, as well as a detailed analysis into the modes of action for different cancer outcomes will be discussed in each chapter wherever deemed feasible. These approaches are ones in which no other book in this area has attempted to do.
650		7	_aCarcinogénesis _2embne _0(OCoLC)fst00852862 _0 _9146492
700	1		_aMudipalli, Anuradha, _eeditor literario
700	1		_aZelikoff, Judith T., _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-55448-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017D
998			_b02/2018 _dz _e- _zSI
999			_c96342 _d96342 _x1