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008			170622s2017 sz ob 001 0 eng d
020			_a3319494791 _q(electronic bk.)
020			_a9783319494791 _q(electronic bk.)
020			_z3319494775
020			_z9783319494777
040			_aN$T _cN$T _dEBLCP _dN$T _dGW5XE _dOCLCF _dYDX _dAZU _dOCLCO _dUPM _dCOO _dOCLCQ _dMERER _dOCLCQ _dOCLCO _dSAV _dJG0 _dUAB _dES-MaUEC _bspa
050		4	_aRE551 _b.C455 2017 EB
245	0	0	_aCellular therapies for retinal disease : _ba strategic approach _cSteven D. Schwartz, Aaron Nagiel, Robert Lanza, editors ; foreword by Mark S. Blumenkranz.
264		1	_aCham _bSpringer _c[2017]
264		4	_c2017
300			_a1 recurso en línea (xiii, 143 páginas)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
500			_aSpringerLink
504			_aIncluye referencias bibliográficas e índice
505	0		_aPart I- Cell Replacement Therapy -- 1. Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cell Transplantation for Retinal Degeneration -- 2. Stem Cell-Derived RPE transplantation: the feasibility and advantages of delivery as monolayers -- 3. Induced Pluripotent Stem Cell-Derived Autologous Cell Therapy for Age-related Macular Degeneration -- 4. Scaffolds for Cell Transplantation -- 5. Surgical Approaches for Cell Transplantation in Cell Replacement Therapy -- 6. Cell Transplantation Therapy for Glaucoma. Part II -- Cell-based Neuroprotection -- 7. Autologous Bone Marrow-Derived Cell Therapies for Retinal Disease -- 8. Subretinal Delivery of Cells Via the Suprachoroidal Space: The Janssen Trial. Part III -- Disease Modeling using Induced Pluripotent Stem Cells -- 9. "Disease in a Dish" Modeling of Retinal Diseases -- 10. Retinal Organoids: An Emerging Technology for Retinal Disease Research and Therapy.
520	3		_aThis book familiarizes the reader with the current landscape of cell-based therapies for the treatment of retinal disease, including diseases that affect the choriocapillaris, retinal pigment epithelium, photoreceptors, and retinal ganglion cells. Instead of utilizing a disease-centric approach to the topic, this book--edited by world-renowned stem cell scientists--focuses on strategies for developing and transplanting the cells. This includes the creation of replacement cells, cell-based neuroprotection, and in vitro disease modeling and testing. The final chapters briefly review parallel approaches that do not directly utilize cellular transplantation. The use of cellular transplantation to treat retinal disease has recently become a viable and exciting therapeutic approach. The visibility of the retina and its laminar cellular architecture render it an ideal organ for the development of surgically delivered cellular therapies. Having an in-depth understanding of the current state of cell therapy for the eye is an essential first step toward utilizing similar approaches in other organs. Ophthalmologists, translational clinician-scientists, stem cell scientists, and researchers interested in eye disease will find Cellular Therapies for Retinal Disease: A Strategic Approach essential reading and it is also suitable for workshops or courses at the undergraduate or Ph. D. level.
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017D
650		7	_aRetina _2embne _0(OCoLC)fst00850322 _9190667 _xEnfermedades
700	1		_aLanza, Robert, _eeditor literario
700	1		_aNagiel, Aaron, _eeditor literario
700	1		_aSchwartz, Steven D., _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-49479-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI