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020 _a3319472666
_q(electronic bk.)
020 _a9783319472669
_q(electronic bk.)
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020 _z9783319472645
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050 4 _aQR177
_b2017 EB
245 0 0 _aAntimicrobial drug resistance
_nVolume 2,
_pClinical and epidemiological aspects
_cDouglas Mayers, Jack D. Sobel, Marc Ouellette, Keith S. Kaye, Dror Marchaim, editors.
246 3 0 _aClinical and epidemiological aspects
250 _aSecond edition
264 1 _aCham, Switzerland
_bSpringer
_c[2017]
300 _a1 recurso en línea
_bilustraciones
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
504 _aIncluye referencias bibliográficas e índice
505 0 _aHistory of Drug-Resistant Microbes -- Evolutionary Biology of Drug Resistance -- Pharmacology of Drug Resistance -- Drug Development for Drug-Resistant Pathogens -- Genetic Mechanisms of Transfer of Drug Resistance -- Mutations as a Basis of Antimicrobial Resistance -- Altered Drug Targets -- Enzymatic Modification of Drugs -- Reduced Drug Penetration -- Active Efflux Mechanism -- Biofilms -- Beta-Lactamases -- Penicillin Binding Proteins -- Aminoglycosides -- Tetracyclines and ChloramphenicolQuinolones -- Plasmid Mediated Quinolone Resistance to Macrolides, Lincosamides, and Streptogramins -- Mechanisms of Resistance in Metronidazole -- Glycopeptide-resistance in eneterococci -- Daptomycin Resistance -- Oxazolidinones -- PolymyxinsSulfonamides and Trimethoprim -- Antimycobacterial Agents -- Amphotericin (Polyenes) -- Azoles -- Flucytosine -- Echinocandins -- Antifungal Targets, Mechanisms of Action, and Resistance in Candida albicans -- Herpes Nucleoside Drugs -- Influenza Drugs -- HIV Nucleoside Drugs -- HIV Non-Nucleoside Drugs -- HIV Protease Inhibitors -- HIV Entry Inhibitors -- HIV Integrase Inhibitors -- Hepatitis B -- Hepatitis C -- Agents for anaerobic protozoa -- Antimalarial Agents -- Agents for Leishmania -- Agents for Trypanosomes -- Agents for Toxoplasma -- Agents for Cryptosporidium -- Agents against Nematodes -- Agents against Trematodes and Cestodes -- Agents against Ectoparasites.
520 3 _aThe two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.
588 0 _aOnline resource; title from PDF title page (EBSCO, viewed June 27, 2017).
988 _aEBOOK, EBSPRINGER_2017D
650 7 _aResistencia a los medicamentos
_2embne
_9146972
700 1 _aKaye, Keith S.,
_eeditor literario
700 1 _aMarchaim, Dror,
_eeditor literario
700 1 _aMayers, Douglas L.,
_eeditor literario
_980372
700 1 _aOuellette, Marc,
_eeditor literario
_945120
700 1 _aSobel, Jack D.,
_eeditor literario
_980374
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-47266-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
880 0 _6505-01/(S
_aPreface; Contents; Contributors; Part VII: Gram Positive Bacterial Drug Resistance: Clinical; 49: Resistance in Streptococcus pneumoniae; 1 Introduction; 2 Epidemiology of the Pneumococcus and Risk Factors for Resistance; 3 The Role of Clones in Resistance; 4 Laboratory Detection of Resistance; 5 Resistance to β-Lactams; 6 Resistance to Macrolides; 7 Resistance to Fluoroquinolones; 8 Resistance to Newer Classes of Antibiotics; 9 Resistance to Other Agents; 10 Clinical Relevance of Antibiotic Resistance; 11 Impact of Conjugate Vaccine; 12 Concluding Remarks; References.
942 _2lcc
_cLE
998 _b06/2019
_dz
_ea
_zSI