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020 _a3319571257
020 _a3319571273
_q(electronic bk.)
020 _a9783319571256
020 _a9783319571270
_q(electronic bk.)
020 _z9783319571256
_q(hardcover ;
_qalk. paper)
040 _aGW5XE
_cGW5XE
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_dYDX
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_dMMU
_dCASUM
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_dAZU
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_dMERER
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050 4 _aQH605
_b.C455 2017 EB
245 0 0 _aCell division machinery and disease
_cMonica Gotta, Patrick Meraldi, editors.
264 1 _aCham, Switzerland
_bSpringer
_c[2017]
264 4 _c2017
300 _a1 recurso en línea (xiv, 235 páginas)
_bilustraciones (algunas a color)
336 _astill image
_bsti
_2rdacontent
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
490 0 _aAdvances in experimental medicine and biology
_x2214-8019
_v1002
500 _aSpringerLink
504 _aIncluye referencias bibliográficas e índice
505 0 _aMeiotic divisions: no place for gender equality / Warif El Yakoubi, Katja Wassmann -- Consequences of centrosome dysfunction during brain development / Maddalena Nano, Renata Basto -- Dividing with extra centrosomes: a double edged sword for cancer cells / Alexander D. Rhys, Susana A. Godinho -- Kinetochore malfunction in human pathologies / Bas de Wolf, Geert J.P.L. Kops -- The elephant in the room: the role of microtubules in cancer / Luca Cirillo, Monica Gotta, Patrick Meraldi -- Clinical development of anti-mitotic drugs in cancer / Anna-Maria Olziersky, S. Intidhar Labidi-Galy -- Mitotic dysfunction associated with aging hallmarks / Joana Catarina Macedo, Sara Vaz, Elsa Logarinho -- Unbalanced growth, senescence and aging / Michael Polymenis, Brian K. Kennedy -- The spindle orientation machinery beyond mitosis: when cell specialization demands polarization / Abigail L.D. Tadenev, Basile Tarc.
520 3 _a"This book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal link between key elements of the cell division machinery and diseases such as cancer, neuropathologies, aging, and infertility. A more clinically oriented chapter further discusses the current and future applications of anti-mitotic drugs in these diseases. Cell Division Machinery and Disease is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases"--Publisher's description.
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017D
650 7 _aDivisión celular
_2embne
_9689279
700 1 _aGotta, Monica,
_eeditor literario
700 1 _aMeraldi, Patrick,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-57127-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2018
_dz
_e-
_zSI