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008			170616s2017 si ob 000 0 eng d
020			_a9789811048098
020			_a9789811048104 _q(electronic bk.)
020			_a9811048096
020			_a981104810X _q(electronic bk.)
020			_z9789811048098
040			_aN$T _cN$T _dN$T _dGW5XE _dOCLCF _dUAB _dYDX _dAZU _dUPM _dMERER _dESU _dOCLCQ _dCOO _dOCLCQ _dVT2 _dIOG _dES-MaUEC _bspa
050		4	_aQP110.V37 _bG369 2017 EB
100	1		_aGao, Yuansheng, _eautor
245	1	0	_aBiology of vascular smooth muscle : _bvasoconstriction and dilatation _cYuansheng Gao.
264		1	_aSingapore _bSpringer _c2017.
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
500			_aSpringerLink _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
504			_aIncluye referencias bibliográficas
505	0		_aArchitecture of the vessel wall -- Ultrastructure of vascular smooth muscle -- Vascular endothelium -- Electrical and mechanical properties of vascular smooth muscle -- Biochemistry of the contractile proteins of smooth muscle -- Metabolism of vascular smooth muscle -- Neurotransmitters -- Endothelium-derived factors -- Local metabolic factors -- Shear stress myogenic response and blood flow autoregulation -- Intracellular Ca2+ regulation -- Regulation of myosin light chain phosphorylation -- Cyclic AMP signalling -- Cyclic GMP signaling -- Coronary vasoreactivity -- Cerebral vasoreactivity -- Pulmonary vasoreactivity -- Hypoxic vasoreactivity -- Ageing and vasoreactivity.
520	3		_aThis book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on recently identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The contraction and dilatation activities of vasculature are of fundamental importance for maintaining circulation homeostasis and adapting physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology.
650		7	_aEnfermería cardiovascular _2embne _0(OCoLC)fst01164503 _0 _9675837
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-981-10-4810-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017D
998			_b02/2018 _dz _e- _zSI
999			_c96185 _d96185 _x1