000			03589cam a2200421Ii 4500
988			_aSpringer_Medicine_2017
999			_c96158 _d96158 _x1
001			96158
003			ES-MaUEC
005			20230102112741.0
006			m o d
007			cr cnu|||unuuu
008			170613s2017 sz a o 001 0 eng d
020			_a3319523546 _q(electronic bk.)
020			_a9783319523545 _q(electronic bk.)
020			_z331952352X
020			_z9783319523521 _q(print)
040			_aGW5XE _cGW5XE _dN$T _dEBLCP _dYDX _dUAB _dAZU _dUPM _dKOS _dMERER _dESU _dOCLCQ _dCOO _dOCLCQ _dIOG _dOCLCO _dOCLCA _dES-MaUEC _bspa
050		4	_aQR185.8.C95 _b2017 EB
245	0	0	_aMIF family cytokines in innate immunity and homeostasis _cRichard Bucala, Jürgen Bernhagen, editors.
264		1	_aCham, Switzerland _bSpringer _c2017.
300			_a1 recurso en línea (viii, 246 páginas) _bilustraciones (algunas a color)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aProgress in Inflammation Research
500			_aIncluye índice
500			_aSpringerLink
505	0		_aMIF and CD74-dependent Mechanisms -- HSP90-stabilized MIF in Oncogenesis and Cell Growth Control- CD74, MIF, and Breast Tumorigenesis: Insights from Recent Large-scale Tumor Genomics and Proteomics Studies -- MIF-dependent Regulation of Monocyte/Macrophage Polarization -- Advances in understanding the role of MIF in the pathogenesis of autoimmune diseases -- Role of MIF in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis -- Role of MIF in Hepatic Inflammatory Diseases and Fibrosis -- MIF and Pulmonary Disease -- MIF Mediates Pelvic Inflammation and Pain -- MIF Family Proteins in Cardiac Ischemia / Reperfusion Injury -- The MIF-CD74 Inflammatory Axis in Alphaviral Infection -- MIF in Eosinophilic Inflammation -- The Role of MIF in Parasitic Infections -- Parasite MIF Orthologs.
520	3		_aThe role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, metabolism, and cellular stress responses. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. New family members, such as D-dopachrome tautomerase, or MIF-2, and the closely homologous genes encoding by parasites have been defined and are being functionally characterized. MIF directed therapies also are entering clinical testing and ultimately may be applied in a pharmacogenomics manner. This book provides a comprehensive synthesis of the state-of-the-art of MIF science. The intended audience are post-graduate students and researchers in inflammation, innate immunity, immunology, and immunopathology.
588	0		_aOnline resource; title from PDF title page (SpringerLink, viewed June 13, 2017).
650		7	_2embne _9162841 _aInmunidad celular
700	1		_aBernhagen, Jürgen, _eeditor literario
700	1		_aBucala, Richard, _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-52354-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI