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020 _a9783319545929
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020 _z3319545906
020 _z9783319545905
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050 4 _aRC112
_b2017 EB
245 0 0 _aImaging infections :
_bfrom bench to bedside
_cSanjay K. Jain, editor.
264 1 _aCham
_bSpringer
_c2017.
300 _a1 recurso en línea (263 páginas)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
500 _a5.2.4 19F-Labeled Perfluorocarbons and€MRI.
500 _aIncluye índice
500 _aSpringerLink
505 0 _aContributors; Chapter 1: Introduction; 1.1 Global Burden of€Infectious Diseases; 1.2 Molecular Imaging; 1.3 The Problem; 1.4 The Solution; 1.5 Biocontainment; 1.6 Human Translation of€PET Tracers; 1.7 Imaging Infections: From€Bench to€Bedside; 1.7.1 Imaging in€the€Clinic; 1.7.2 Molecular Imaging Techniques; 1.7.3 Imaging Host Responses; 1.7.4 Pathogen-Specific Tracers; 1.7.5 Neuroimaging; 1.7.6 Antimicrobial Development; 1.7.7 Image Analyses; 1.7.8 Imaging in€the€Developing World; 1.8 Summary; References; Chapter 2: Clinical Imaging; 2.1 Introduction; 2.2 Anatomical Imaging Tests.
505 8 _a2.2.1 Computed Tomography2.2.2 Magnetic Resonance Imaging; 2.2.3 Ultrasonography; 2.3 Molecular Imaging Tests; 2.3.1 Nonspecific Agents; 2.3.1.1 Single-Photon-Emitting (SPECT) Radiopharmaceuticals; Gallium-67 Citrate; Labeled Leukocytes; 2.3.1.2 Positron-Emitting Radiopharmaceuticals; 18F-FDG; Other PET Radiopharmaceuticals; Gallium-68 Citrate; 2.3.2 Infection-Specific Agents; 2.3.2.1 SPECT Radiopharmaceuticals; Radiolabeled Antibiotics; 111In-Biotin; Radiolabeled Antimicrobial Peptides; 2.3.2.2 PET Radiopharmaceuticals; 2.4 Summary; References; Chapter 3: Optical Imaging; 3.1 Introduction.
505 8 _a3.2 Bioluminescent Imaging3.3 Fluorescence Imaging; 3.4 Development of€Bioluminescent and€Fluorescent Microorganisms; 3.5 Bacterial Imaging; 3.6 Fungal Imaging; 3.7 Parasite Imaging; 3.8 Viral Imaging; 3.9 Translation to€the€Clinic; 3.9.1 Bacterial Surface Probes; 3.9.2 Antibiotic Probes; 3.9.3 Bacteriophage and€Antibody Probes; 3.9.4 Metabolizable Probes; 3.9.5 Activatable Probes; 3.10 Photoacoustic Imaging; 3.11 Multimodality Imaging; 3.12 Photodynamic Therapy; 3.13 Conclusions and€Future Directions; 3.14 Summary; References; Chapter 4: Radiochemistry; 4.1 Introduction; 4.2 Radionuclides.
505 8 _a4.2.1 Iodine Radionuclides4.2.2 Carbon-11 (C-11, 11C); 4.2.3 Fluorine-18 (F-18, 18F); 4.2.4 Technetium-99m (Tc-99m, 99mTc); 4.2.5 Copper-64 (Cu-64, 64Cu); 4.2.6 Gallium-68 (Ga-68, 68Ga); 4.2.7 Gallium-67 (Ga-67, 67Ga); 4.2.8 Indium-111 (In-111, 111In); 4.3 Examples of€Infection Imaging Agents; 4.3.1 67Ga-Citrate SPECT; 4.3.2 111In-Oxine-Leukocyte SPECT; 4.3.3 99mTc-HMPAO-Leukocyte-SPECT (CERETEC®); 4.3.4 18F-FDG PET; 4.3.5 99mTc-Sn-Colloid SPECT (Leukocyte®); 4.3.6 99mTc-MDP SPECT; 4.3.7 99mTc-Besilesomab SPECT (Scintimun®); 4.3.8 99mTc-Sulesomab SPECT (LeukoScan®).
505 8 _a4.3.9 99mTc-Sulfur-Nanocolloids SPECT (Nanocoll®)4.4 Experimental Radiotracers for€Infection Imaging; 4.4.1 Synthetics and€Biomimetics; 4.4.2 Antibiotics; 4.4.3 Radiolabeled Cells; 4.4.4 Bacteria-Specific Sugars; 4.4.5 Macromolecules and€Antibodies; 4.4.6 Small Peptide Fragments; 4.4.7 Other Agents; 4.5 Summary; References; Chapter 5: Imaging the€Host Response; 5.1 Introduction; 5.2 Leukocyte Tracking; 5.2.1 [111In]Oxyquinoline and€[99mTc]HMPAO; 5.2.2 18F-2-Fluoro-Deoxy-d-Glucose (18F-FDG) Ex Vivo Labeling of€Leukocytes; 5.2.3 Iron Oxide Nanoparticle Labeling and€T2-Weighted MRI.
520 3 _aThis books brings together multi-disciplinary expertise to provide comprehensive information about molecular imaging of infectious diseases. Also described are the development of new imaging technologies for infectious disease and their translation to the clinic. The overall goal of Imaging Infections: From Bench to Bedside is to spur interest and innovation in this emerging field. We anticipate that these technologies will not only allow unique insights into understanding pathogenesis of infections but also expedite bench-to-bedside translation of new therapeutics. While molecular imaging is already in common use in the clinic, this book demonstrates how it could also become a valuable tool for clinical studies, patient care, public health, and for enabling precision medicine for infectious diseases.
650 7 _2embne
_aEnfermedades infecciosas
_9138404
700 1 _aJain, Sanjay K.
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-54592-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2018
_dz
_e-
_zSI