000			05491cam a2200421Ii 4500
999			_c96117 _d96117 _x1
001			96117
003			ES-MaUEC
005			20230102112739.0
006			m o d
007			cr |||||||||||
008			170602t20172017sz a ob 001 0 eng d
020			_a3319559478 _q(electronic bk.)
020			_a9783319559476 _q(electronic bk.)
020			_z331955946X _q(hardcover : alk. paper)
020			_z9783319559469 _q(hardcover : alk. paper)
040			_aYDX _cYDX _dN$T _dEBLCP _dMMU _dOCLCO _dN$T _dGW5XE _dYDX _dOCLCO _dUAB _dESU _dAZU _dUPM _dOCLCF _dOCLCO _dIOG _dOCLCO _dCOO _dCASUM _dOCLCO _dMERER _dOCLCQ _dAUD _dTFH _dOCLCO _dOCLCQ _dJG0 _dOCLCO _dOCLCQ _dU3W _dOCLCO _dOCLCA _dES-MaUEC _bspa
050		4	_aRC269.5 _bI865 2017 EB
245	0	0	_aIsolation and molecular characterization of circulating tumor cells _cMark Jesus M. Magbanua, John W. Park, editors.
264		1	_aCham, Switzerland _bSpringer _c[2017]
264		4	_c2017
300			_a1 recurso en línea (xvi, 301 páginas) _bilustraciones (algunas a color)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aAdvances in experimental medicine and biology _x2214-8019 _v994
500			_aSpringerLink
504			_aIncluye referencias bibliográficas e índice
505	0		_aCirculating tumor cells as cancer biomarkers in the clinic / Ludmilla Thomé Domingos Chinen, Emne Ali Abdallah, Alexcia Camila Braun [and others] -- Strategies for isolation and molecular profiling of circulating tumor cells / Jia-Yang Chen, Ying-Chih Chang -- Aptamer-based methods for detection of circulating tumor cells and their potential for personalized diagnostics / Anna S. Zamay, Galina S. Zamay, Olga S. Kolovskaya, Tatiana N. Zamay [and others] -- Development of a protocol for single-cell analysis of circulating tumor cells in patients with solid tumors / Carolina Reduzzi, Rosita Motta, Giulia Bertolini, Patrizia Miodini, Antonia Martinetti [and others] -- Flow cytometric methods for circulating tumor cell isolation and molecular analysis / Neha Bhagwat, Erica L. Carpenter -- Enrichment and detection of circulating tumor cells and other rare cell populations by microfluidic filtration / Michael Pugia, Mark Jesus M. Magbanua, John W. Park -- Detection and enumeration of circulating tumor cells with invasive phenotype / Haizhen Wang, Xiangwei Wu -- Molecular profiling and significance of circulating tumor cell based genetic signatures / Nisha Kanwar, Susan J. Done -- Detection of gene rearrangements in circulating tumor cells: examples of ALK-, ROS1-, RET-rearrangements in non-small-cell lung cancer and ERG-rearrangements in prostate cancer / Cyril Catelain, Emma Pailler, Marianne Oulhen, Vincent Faugeroux, Anne-Laure Pommier [and others] -- Enrichment, isolation and molecular characterization of EpCAM-negative circulating tumor cells / Rita Lampignano, Helen Schneck, Martin Neumann, Tanja Fehm, Hans Neubauer -- Expression of epithelial mesenchymal transition and cancer stem cell markers in circulating tumor cells / Stefan Werner, Arnulf Stenzl, Klaus Pantel, Tilman Todenh̲fer -- Mesenchymal-epithelial transition and circulating tumor cells in small cell lung cancer / Gerhard Hamilton, Barbara Rath -- Clinical relevance of a candidate stem cell marker, p75 neurotrophin receptor (p75NTR) expression in circulating tumor cells / Tomoyuki Okumura, Tetsuji Yamaguchi, Toru Watanabe, Takuya Nagata, Yutaka Shimada -- Personalized treatment through detection and monitoring of genetic aberrations in single circulating tumor cells / Swee Jin Tan, Trifanny Yeo, Sarvesh Abhay Sukhatme, Say Li Kong, Wan-Teck Lim [and others] -- Glycan markers as potential immunological targets in circulating tumor cells / Denong Wang, Lisa Wu, Xiaohe Liu -- Significance of EGFR expression in circulating tumor cells / María José Serrano, María Jesús Alvarez-Cubero, Diego De Miguel Pérez [and others].
520	3		_a"Numerous studies have shown that elevated levels of circulating tumor cells (CTCs) in blood of cancer patients are associated with poor response to treatment and inferior survival probabilities. Despite this clinical significance, the molecular biology of CTCs remains poorly understood. The paucity in molecular information can be attributed to the tremendous technical challenges involved in isolating these extremely rare cells. Recent technological advancements in rare-cell technology, however, have allowed for the reliable enrichment and isolation of CTCs. Consequently, the use of recently developed molecular approaches -e.g., multiplexed QPCR, microarray, and next generation sequencing analyses- to profile CTCs have provided novel insights into the molecular makeup of these tumor cells. This book discusses approaches for enrichment and isolation of CTCs as well as recent advances in comprehensive molecular profiling of CTCs using cutting-edge omics technology"--Publisher's description.
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017D
650		7	_aMetastasis. _2fast _0(OCoLC)fst01018329 _9413460
700	1		_aMagbanua, Mark Jesus M., _eeditor literario
700	1		_aPark, John W., _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-55947-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI