000			05187cam a2200469Ki 4500
988			_aSpringer_Medicine_2017
999			_c96073 _d96073 _x1
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005			20230102112737.0
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007			cr |n|||||||||
008			170530s2017 sz o 001 0 eng d
020			_a3319452312 _q(electronic bk.)
020			_a9783319452319 _q(electronic bk.)
020			_z3319452304
020			_z9783319452302
040			_aYDX _cYDX _dN$T _dEBLCP _dGW5XE _dN$T _dAZU _dUAB _dUPM _dOCLCF _dCOO _dMERER _dESU _dOCLCQ _dIOG _dOHI _dES-MaUEC _bspa
050		4	_aRC280 U8 _b2017 EB
066			_c(S
245	0	0	_aCervical cancer _cJaime G. de la Garza-Salazar, Flavia Morales-Vásquez, Abelardo Meneses-Garcia, editors.
264		1	_aCham, Switzerland _bSpringer _c2017.
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
500			_aIncluye índice
500			_aSpringerLink
505	0		_aPreface; Acknowledgments; About the Editors ; Contents; Contributors; Chapter 1: Introduction; 1.1 History of the Vaginal Cytology; 1.2 History of the Vaginal Cytology in Mexico; 1.3 The Work Submitted to the Mexican Association of Gynecology and Obstetrics (1945), the References Uses Obsolete Parameters; 1.4 Chemotherapy and Concomitant Radiotherapy for Cervical Cancer; 1.5 The Sexuality of CxCa Patients; 1.6 Other Primary Tumors of the Cervix; 1.6.1 Epithelial Lineage Tumors; 1.6.2 Neuro-endocrine Tumors; 1.6.3 Mesenchymatous-Origin Tumors; 1.7 Metastatic Tumors on to the Cervix; References.
505	8		_6880-01 _a5.6 Natural History of HPV Infection; 5.7 Screening; 5.8 Nomenclature; 5.9 Approach and Treatment of Pre-invasive Lesions; 5.9.1 Colposcopic Evaluation; 5.9.2 Treatment Generalities; 5.9.3 Atypical Squamous Cells of Uncertain Significance (ASC-US) and Low-Grade Intra-epithelial Lesions; 5.9.4 High-Grade Intra-epithelial Lesion; 5.9.5 Glandular Lesions; 5.10 Treatment Options; 5.11 Conclusion; References; Chapter 6: Control and Prevention in Cervical Cancer; 6.1 Introduction; 6.2 Review of the Governmental Response in Recent Years.
505	8		_a3.3 Genomic Integration of HPV and Host Genomic Instability Induction as Basic Steps toward Malignant Transformation by HPV; 3.4 Telomerase Activation as Molecular Transformation and Immortalization Mechanisms by HPV; 3.5 Metabolic Tumor Adaptations as HPV Transforming Mechanisms; 3.6 Cervical Host Infections Patterns (Oncobioma) of Malignant Precursor Lesions and Tumor Microenvironment as Promoters and Enhancers of HPV Transforming Mechanisms; References; Chapter 4: Transcriptome Studies Reveal Altered Signaling Pathways in Cervical Cancer; 4.1 Introduction.
505	8		_aChapter 2: Cervical Cancer Epidemiology; 2.1 Impact of Cervical Cancer (CC); 2.1.1 In the World; 2.1.2 Latin America and the Caribbean; 2.1.3 In Mexico; 2.1.3.1 Morbidity; 2.1.3.2 Mortality; 2.2 Risk Factors; 2.3 Evolution of the Cervical Cancer Program in Mexico; 2.4 The Role of the Health Care System in Mexico to Prevent Mortality and Morbidity Due to Cervical Cancer: Conclusions; References; Chapter 3: Malignant Transforming Mechanisms of Human Papillomavirus; 3.1 HPV Generalities, Life Cycle and Genome; 3.2 Transforming Mechanisms of HPV Viral Oncoproteins.
520	3		_aThis book provides readers with a thorough review on cervical cancer, treatment guidelines and emerging therapies available for the disease. It reviews the epidemiology clinical features, diagnosis, and medical management of cervical cancer. Given the increasing need for preventive strategies, treatment optimization with collaborative and integrative work, this book improves the actual and integral knowledge in this neoplasm. Given the high prevalence of this disease in Latin America, this is an important text for clinicians in this region. This book outlines the state of the art in cervical cancer treatments and is an indispensable companion for oncologists, gynecologists, surgeons and medical students.
650		7	_aCuello uterino _xCáncer _2embne _9212741
700	1		_aGarza-Salazar, Jaime G. de la.
700	1		_aMeneses García, Abelardo.
700	1		_aMorales-Vásquez, Flavia.
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-45231-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
880	8		_6505-01/(S _a4.2 Nuclear Factor Kappa B (NF-κB) Pathway; 4.2.1 HPV Infection Induces NF-κB Activation; 4.3 Regulation of Tumor Growth Factor ß (TGF-ß); 4.3.1 Differential Expression Profiles in the TGF-ß Pathway; 4.4 Wnt/ß-Catenin Pathway Activation in CxCa; 4.5 Role of the Mitogen-Activated Protein Kinase (MAPK) Pathway; 4.5.1 MAPK Signaling Pathway Component Expression in Cervical Cancer; 4.6 Conclusions; References; Chapter 5: Pre-invasive Lesions of the Cervix; 5.1 Introduction; 5.2 Epidemiology; 5.3 Risk Factors for the Development of Pre-invasive Lesions; 5.4 Human Papilloma Virus; 5.5 Vaccines.
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI