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008 170511s2017 sz o 000 0 eng d
020 _a3319533169
_q(electronic bk.)
020 _a9783319533162
_q(electronic bk.)
020 _z3319533142
020 _z9783319533148
_q(print)
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_bspa
050 4 _aQM567
_b.C378 2017 EB
245 0 0 _aCartilage
_nVolume 3,
_pRepair strategies and regeneration
_cSusanne Grässel, Attila Aszódi, editors.
246 3 0 _aRepair strategies and regeneration
264 1 _aCham, Switzerland
_bSpringer
_c2017.
300 _a1 recurso en línea
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
500 _aSpringerLink
505 0 _aPreface; Contents; List of Contributors; 1: Overview: State of the Art and Future Prospectives for Cartilage Repair; 1.1 Introduction; 1.1.1 Clinical Relevance and Needs of Cartilage Repair; 1.2 Cartilage Structure, Function, and Injuries; 1.2.1 Cartilage Structure; 1.2.2 Cartilage Injury; 1.2.3 Clinical Outcomes of Treatments; 1.3 Current Cartilage Repair Strategies; 1.3.1 Palliative Approach: Arthroscopic Debridement/Lavage; 1.3.2 Intrinsic Repair: Bone Marrow Stimulation Technique-Abrasion, Drilling, and Microfracture.
505 8 _a1.3.3 Whole Tissue Transplantation: Osteochondral Graft Transplantation1.3.4 Tissue-Engineered Cartilage; 1.3.4.1 Autologous Chondrocyte Implantation/Transplantation (ACI/ ACT); 1.3.5 Total Joint Replacement; 1.4 New Strategies Under Investigation; 1.4.1 Cell-Based Therapies; 1.4.1.1 Stem Cells; Stem Cell Types Relevant to Cartilage Repair; Signaling Factors: Stem Cell Differentiation and Cell Phenotype Maintenance; 1.4.1.2 Allogeneic Chondrocytes; 1.4.2 Biomaterial Scaffolds for Cartilage Repair; 1.4.2.1 Current Biomaterials and 3D Scaffolds.
505 8 _a1.4.2.2 Major Concerns in Scaffold Design1.5 Unsolved Problems and Challenges in Cartilage Repair; 1.5.1 Tissue Integration; 1.5.2 Maintenance of Cell Phenotype; 1.5.3 Simplifying Surgical and Rehabilitation Procedures; 1.5.4 Prevention of OA Progress; 1.5.4.1 Establishing Correct Joint Mechanical Environment; 1.5.4.2 Rebuilding Subchondral Bone; 1.5.4.3 Anti-Inflammatory Actions; References; 2: MSC Populations for Cartilage Regeneration; 2.1 Embryonic Origin of Chondroprogenitor Cells (CPCs); 2.2 In Vivo Presence of MSCs in Adult Joints; 2.2.1 Characteristics of MSCs In Vivo.
505 8 _a2.2.1.1 Articular Cartilage-Derived Chondroprogenitor cells (CPCs)2.2.1.2 Bone Marrow-Derived MSCs (BMSCs); 2.2.1.3 Synovium-Derived MSCs (SM-MSCs); 2.2.1.4 Synovial Fluid-Derived MSCs (SF-MSCs); 2.2.1.5 Infrapatellar Fat Pad-Derived MSCs (IF-MSCs); 2.2.2 Contribution to Repair by MSCs In Vivo; 2.3 MSCs In Vitro; 2.3.1 Articular Cartilage-Derived MSCs (AC-MSCs); 2.3.2 Bone Marrow-Derived MSCs (BMSCs); 2.3.3 Synovium-Derived MSCs (SM-MSCs); 2.3.4 Synovial Fluid-Derived MSCs (SF-MSCs); 2.3.5 Infrapatellar Fat Pad-Derived MSCs (IF-MSCs).
505 8 _a2.4 Manipulation of Joint Stem Cell Phenotype In Vitro by Growth FactorsReferences; 3: Chondrogenic Progenitor Cells and Cartilage Repair; 3.1 Osteoarthritis and Rheumatoid Arthritis; 3.2 Regeneration Attempts in Cartilage Tissue; 3.2.1 Mesenchymal Stem Cells and Osteoarthritis; 3.2.2 Mesenchymal Stem Cells and Rheumatoid Arthritis; 3.3 Chondrogenic Progenitor Cells; 3.3.1 Chondrogenic Progenitor Cells from Osteoarthritic Patients (CPCs); 3.3.2 Chondrogenic Progenitor Cells from Rheumatoid Arthritis Patients; 3.3.3 Meniscus Progenitor Cells (MPCs); References.
520 3 _aIn three Volumes this mini book series presents current knowledge and new perspectives on cartilage as a specialized yet versatile tissue. This third volume provides insight into current and future treatment strategies for repair of cartilage lesions. This book addresses Professors, researchers and PhD students who are interested in musculoskeletal and cartilage pathobiology and tissue-engineering.
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017D
650 7 _aTejidos (Biología)
_xRegeneration.
_2embne
_0(OCoLC)fst01909355
_9668849
700 1 _aAszódi, Attila
_eeditor literario
_998680
700 1 _aGrässel, Susanne
_eeditor literario
_998679
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-53316-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2018
_dz
_e-
_zSI