| 000 | 05446cam a2200421Ii 4500 | ||
|---|---|---|---|
| 001 | 95960 | ||
| 003 | ES-MaUEC | ||
| 005 | 20230102112731.0 | ||
| 006 | m o d | ||
| 007 | cr cnu|||unuuu | ||
| 008 | 170510s2017 gw a o 001 0 eng d | ||
| 020 | _a3662471809 | ||
| 020 |
_a3662471817 _q(electronic bk.) |
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| 020 | _a9783662471807 | ||
| 020 |
_a9783662471814 _q(electronic bk.) |
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| 020 |
_z9783662471807 _q(print) |
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| 040 |
_aN$T _cN$T _dYDX _dGW5XE _dEBLCP _dN$T _dOCLCF _dOCLCO _dUAB _dESU _dAZU _dUPM _dIOG _dOCLCO _dCOO _dMERER _dOCLCO _dVT2 _dOCLCQ _dOCLCO _dOCLCA _dU3W _dOCLCO _dES-MaUEC _bspa |
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| 050 | 4 |
_aRC280.P25 _b2017 EB |
|
| 245 | 0 | 0 |
_aPancreatic cancer : _bwith special focus on topical issues and surgical techniques _cSun-Whe Kim, Hiroki Yamaue, editors. |
| 264 | 1 |
_aBerlin, Germany _bSpringer International Publishing _c2017 |
|
| 300 |
_a1 recurso en línea (xvii, 472 páginas) _bilustraciones (algunas a color) |
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| 336 |
_aTexto _btxt _2rdacontent |
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| 337 |
_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF |
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| 505 | 0 | _aPreface; Contents; List of Editors; Contributors; Part I: Pathology and Tumor Biology; 1: Epidemiology; 1.1 Epidemiology of Pancreatic Cancer; 1.1.1 Incidence; 1.1.2 Mortality; 1.1.3 Survival; 1.1.4 Risk Factors; References; 2: Molecular Alterations in Pancreatic Cancer; 2.1 Introduction; 2.2 Genetic Alterations in PDAs; 2.3 KRAS and the Mitogen-ƯActivated Protein Kinase Pathway; 2.4 TP53; 2.5 CDKN2A; 2.6 SMAD4; 2.7 Chromatin Modification Genes; 2.8 DNA Repair-Associated Genes; 2.9 RNA Processing Genes; 2.10 Wnt Pathway Genes. | |
| 505 | 8 | _a2.11 Phosphatidylinositol 3-Kinase (PI3K) Pathway Genes2.12 Molecular Mechanism of Development of PDA; 2.13 Genetic Alterations in Intraductal Papillary Mucinous Neoplasms; 2.14 Familial Pancreatic Cancer; 2.15 Implication of Molecular Alterations in Clinical Practice; References; 3: Pathological Classification; 3.1 Ductal Neoplasms; 3.1.1 Invasive Ductal Adenocarcinoma; 3.1.2 Pancreatic Intraepithelial Neoplasia (PanIN); 3.1.3 Other Carcinomas of Ductal Origin; 3.1.4 Intraductal Neoplasms; 3.1.4.1 Intraductal Papillary Mucinous Neoplasms. | |
| 505 | 8 | _a3.1.4.2 Intraductal Tubulopapillary Neoplasms3.1.5 Mucinous Cystic Neoplasms; 3.1.6 Serous Cystic Tumors; 3.1.7 Pancreatic Neuroendocrine Tumors; 3.1.8 Acinar Neoplasms; 3.1.9 Solid Pseudopapillary Neoplasm; 3.1.10 Pancreatoblastoma; 3.1.11 Miscellaneous Cystic Pancreatic Lesions; 3.1.12 Pseudotumors; 3.1.13 Mesenchymal Tumors; 3.1.14 Secondary Tumors; References; 4: Controversial Issues in Pathological Diagnosis; References; 5: Operative Specimen Handling and Evaluation of Resection Margins; 5.1 Introduction; 5.2 Specimen Orientation and External Inspection. | |
| 505 | 8 | _a5.2.1 Pancreatoduodenectomy Specimens5.2.1.1 Specimen Orientation; 5.2.1.2 External Examination; 5.2.2 Distal Pancreatectomy Specimens; 5.3 Specimen Fixation; 5.3.1 Specimen Handling Prior to Fixation; 5.3.2 Specimen Fixation; 5.4 Inking of the Specimen Surface; 5.5 Specimen Dissection; 5.5.1 Axial Slicing of Pancreatoduodenectomy Specimens; 5.5.2 Advantages of the Axial Slicing Technique; 5.5.3 Dissection of Distal and Total Pancreatectomy Specimens; 5.5.4 Dissection of Extended Pancreatectomy Specimens; 5.6 Macroscopic Examination. | |
| 505 | 8 | _a5.6.1 Identification of Anatomical Structures in Pancreatoduodenectomy Specimens5.6.2 Identification of Anatomical Structures in Distal Pancreatectomy Specimens; 5.6.3 Macroscopic Description; 5.7 Photodocumentation; 5.8 Tissue Sampling; 5.8.1 Sampling Technique; 5.8.2 Sampling of Transection Margins; 5.8.3 Sampling from Specimens with Venous or Arterial Resection; 5.8.4 Sampling from Extended Pancreatic Resection Specimens; 5.8.5 Routinely Sampled Tissues; 5.8.6 Block Key; 5.9 Assessment of the Margin Status; 5.9.1 Macroscopic Examination. | |
| 520 | 3 | _aThis book provides state of the art knowledge on a broad range of clinical issues in pancreatic cancer, covering topics from screening and pathophysiology to surgical treatments. In particular, the focus is on current controversies and on evidence-based surgical techniques. Further aspects considered include the management of precancerous lesions, diagnostic methods, perioperative care and nonsurgical treatment. The description of surgical methods is supported by many helpful illustrations and important technical issues are carefully addressed. Determination of resectability and extent of surgery is also discussed. Based on recent developments in surgical techniques, some surgeons are performing more and more radical operations. It is essential, however, that surgical strategy is based on the best available evidence and surgeons will find that this book offers valuable help in achieving this aim. In addition, it will be a great asset in clinical practice for all who are involved or interested in the management of pancreatic cancer. | |
| 650 | 7 |
_aPancreas _xCancer _xSurgery. _2fast _0(OCoLC)fst01051976 _9194247 _0comprobar BNE19923105795 |
|
| 700 | 1 |
_aKim, Sun-Whe, _eeditor literario |
|
| 700 | 1 |
_aYamaue, Hiroki, _eeditor literario |
|
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-662-47181-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 988 | _aSpringer_Medicine_2017 | ||
| 998 |
_b02/2018 _dz _e- _zSI |
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| 999 |
_c95960 _d95960 _x1 |
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