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020 _a3319538802
_q(electronic bk.)
020 _a9783319538808
_q(electronic bk.)
020 _z3319538799
020 _z9783319538792
_q(print)
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050 4 _aRS431.A64
_bB568 2017 EB
066 _c(S
245 0 0 _aBiotechnology and production of anti-cancer compounds
_cSonia Malik, editor.
264 1 _aCham, Switzerland
_bSpringer
_c2017.
300 _a1 recurso en línea (xv, 328 páginas)
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aIncluye índice
500 _aSpringerLink
_bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505 0 _6880-01
_aDedication; Preface; Acknowledgments; Contents; Contributors; Chapter 1: Medicinal Plants: Ethno-Uses to Biotechnology Era; Historical Background; Ethnomedicines Uses of Herbs Between the Past and the Present; Ancient Times; In Egypt; In Greece; In China; In India; Middle Ages; Arabic Achievements in Herbal Medicine; Modern Era; Early Modern Era; Turning Points in the Use of Medicinal Plants; Importance of Medicinal Plants Has Increased Recently ... Why?; Why the Need Arises to Search for New Sources of Drugs?; Economic Returns for the Use of Medicinal Plants.
505 8 _aChapter 2: How Plants Can Contribute to the Supply of Anticancer Compounds Introduction; Plant Secondary Metabolites as Anticancer Drugs; Natural Sources of Plant Metabolites with Anticancer Activity; Production of Small-Molecule Anticancer Compounds in Plants; Protein-Based Anticancer Compounds from Plants; Anticancer Activity of Lectins; Recombinant Protein Expression in Plants; Benefits and Challenges; Product Recovery and Purification; Process Design and Monitoring; Transgenic Plants and the Potential Large-Scale Production of Anticancer Compounds.
505 8 _aHow to Use the Herbal Medicines? Awareness in the Use of Medicinal Plants; Regulation and Legislation of Herbal Medicines; Medicinal Plants Were Used Traditionally to Heal from Cancer: Why? and How?; Why People Use Herbal Medicine with Cancer?; Medicinal Plants: Cancer Remedies Between the Past and the Present; Herbal Medicines: Traditional Treatment of Cancer Worldwide; New Vision of Medicinal Plants by Biotechnological Lenses; How Will the Medicinal Plants Be Drugs?; Background of Knowledge; Plant Selection; Preparation and Isolation of Bioactive Substances.
505 8 _aThe Need of Pharmacological Validation Benefits of Applying Biotechnology in Medicinal Plants; Why It Has Increased the Need to Apply Biotechnology to Medicinal Plants?; What Are the Advantages of Applied Biotechnological Techniques?; Trace Medicinal Plants from Field to Fork by Biotech Approaches ... Is It Possible?; Determine the Geographical Origin of Herbal Materials Is Vital Requirement ... Why?; Current Techniques Used for Determining the Origin of Medicinal Plants; PCR-DGGE: Innovative Biological Barcode of Medicinal Plants; Conclusion and Future Prospects; References.
520 3 _aThis book discusses cancers and the resurgence of public interest in plant-based and herbal drugs. It also describes ways of obtaining anti-cancer drugs from plants and improving their production using biotechnological techniques. It presents methods such as cell culture, shoot and root culture, hairy root culture, purification of plant raw materials, genetic engineering, optimization of culture conditions as well as metabolic engineering with examples of successes like taxol, shikonin, ingenol mebutate and podophylotoxin. In addition, it describes the applications and limitations of large-scale production of anti-cancer compounds using biotechnological means. Lastly, it discusses future economical and eco-friendly strategies for obtaining anti-cancer compounds using biotechnology.
650 7 _aAntineoplásicos
_2embne
_0(OCoLC)fst00810595
_0
_9405304
700 1 _aMalik, Sonia,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-53880-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
880 8 _6505-01/(S
_aScalability and Product Quality Monoclonal Antibodies; Lectins; Anticancer Vaccines; Transient Expression Systems for Individualized Cancer Therapies; Conclusions; References; Chapter 3: Cancer and Biotechnology: A Matchup that Should Never Slowdown; Introduction; Cancer Stem Cells; CSCs Self-Renewal Pathways; Wnt/β-Catenin Pathway; Notch Pathway; Hedgehog Pathway; CSCs Niche; Hypoxia; Inflammation; Three-Dimensional Tumor Spheroid Models; Cytotoxic and Antiproliferative Effects of Natural Products and Derivatives Against Tumor Spheroid Models.
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017C
998 _b02/2018
_dz
_e-
_zSI
999 _c95870
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