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020 _a3319532359
_q(electronic bk.)
020 _a9783319532356
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020 _z3319532332
020 _z9783319532332
_q(print)
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050 4 _aRC271.R3
_b2017 EB
066 _c(S
245 0 0 _aAdvances in radiation oncology
_cJeffrey Y.C. Wong, Timothy E. Schultheiss, Eric H. Radany, editors.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (viii, 271 páginas)
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 0 _aCancer treatment and research
_x0927-3042
_vvolume 172
505 0 _6880-01
_aUse of Multi-parametric MRI in Radiotherapy -- MRI Guided Radiotherapy -- MRI Guided Focused Ultrasound and Thermal Oncology -- Use of PET and Novel Molecular Imaging in IGRT -- The Impact of IGRT on Normal Tissue Toxicity -- Image Guided Brachytherapy -- Hypofractionated IGRT for the treatment of primary cancers -- SBRT and the treatment of oligometastatic disease -- Molecular and image guided systemic targeted radiotherapy -- Integrating Radiotherapy and Immunotherapy -- Biomarkers and Radiotherapy -- Application of Mathematical and Systems Biology to Radiotherapy -- The Importance of Cancer Stem Cells in Radiotherapy -- Targeting DNA repair mechanisms in radiotherapy.
520 3 _aThis book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology. It explores in detail the impact of newer imaging modalities, such as multiparametric magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodeoxyglucose (FDG) and other novel agents, which deliver improved visualization of the physiologic and phenotypic features of a given cancer, helping oncologists to provide more targeted radiotherapy and assess the response. Due consideration is also given to how advanced technologies for radiation therapy delivery have created new treatment options for patients with localized and metastatic disease, highlighting the increasingly important role of image-guided radiotherapy in treating systemic and oligometastatic disease. Further topics include the potential value of radiotherapy in enhancing immunotherapy thanks to the broader immune-stimulatory effects, how cancer stem cells and the tumor microenvironment influence response, and the application of mathematical and systems biology methods to radiotherapy.
650 7 _aCancer
_xImaging.
_2fast
_0(OCoLC)fst00845381
_9139308
_0comprobar BNE19900970859
700 1 _aRadany, Eric H.,
_eeditor literario
700 1 _aSchultheiss, Timothy E.,
_d1951-
_eeditor literario
700 1 _aWong, Jeffrey Y. C.,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-53235-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
880 0 _6505-01/(S
_aPreface; Contents; 1 Combining Radiotherapy and Immunotherapy; Abstract; 1 Radiation Therapy Effects on the Immune System; 1.1 Immunostimulatory Activity of Radiation Therapy; 1.2 Immunosuppressive Effects of Radiation Therapy; 2 Pre Clinical and Clinical Combinations of Radiotherapy and Immune Agents; 2.1 Toll-like Receptor (TLR) Agonists; 2.2 Cancer Vaccines; 2.3 GM-CSF; 2.4 TGF-β Antagonist; 2.5 CTLA-4 Blockade; 2.6 PD-1/PD-L1; 3 Optimizing Radiation Dose and Fractionation; 4 Future Directions; 4.1 CSF-1/CSF-1R; 4.2 OX40; 5 Conclusion; References.
988 _aSpringer_Medicine_2017
998 _b02/2018
_dz
_e-
_zSI
999 _c95858
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