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020 _a9783319531502
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020 _z3319531492
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050 4 _aQH605
_b.A896 2017 EB
245 0 0 _aAsymmetric cell division in development, differentiation and cancer
_cJean-Pierre Tassan, Jacek Z. Kubiak, editors.
264 1 _aCham, Switzerland
_bSpringer
_c2017.
300 _a1 recurso en línea (vi, 421 páginas)
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 0 _aResults and problems in cell differentiation
_x0080-1844
_vvolume 61
500 _aSpringerLink
504 _aIncluye referencias bibliográficas
520 3 _aThis book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017C
650 7 _aDivisión celular
_2embne
_9689279
700 1 _aKubiak, Jacek Z.,
_eeditor literario
700 1 _aTassan, Jean-Pierre,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-53150-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
880 0 _6505-00/(S
_a1 Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach -- 2 Spatiotemporal models of asymmetric cell division cycle in Caulobacter crescentus -- 3 Intrinsic and extrinsic determinants linking spindle pole fate, spindle polarity and asymmetric cell division in the budding yeast S. cerevisiae -- 4 Wnt signaling polarizes C. elegans asymmetric cell divisions during development -- 5 Asymmetric cell division in the one-cell C.elegans embryo: multiple steps to generate cell size asymmetry -- 6 Size matters: how C. elegans asymmetric divisions regulate apoptosis -- 7 The midbody and its remnant in cell polarization and asymmetric cell division -- 8 Drosophila melanogaster neuroblasts: a model for asymmetric stem cell divisions -- 9 Asymmetric divisions in oogenesis -- 10 Asymmetric localization and distribution of factors determining cell fate during early development of Xenopus laevis -- 11 Asymmetries in cell division, cell size and furrowing in the Xenopus laevis embryo -- 12 Asymmetric and unequal cell divisions in ascidian embryos -- 13 Asymmetries and symmetries in the mouse oocyte and zygote -- 14 Symmetry does not come for free -- cellular mechanisms to achieve a symmetric cell division -- 15 A Comparative Perspective on Wnt/β-catenin Signalling in Cell Fate Determination -- 16 Extracellular regulation of the mitotic spindle and fate determinants driving asymmetric cell division -- 17 Regulation of asymmetric cell division in mammalian neural stem and cancer precursor cells -- 18 Molecular programs underlying asymmetric stem cell division and their disruption in malignancy.
942 _2lcc
_cLE
998 _b02/2018
_dz
_e-
_zSI