| 000 | 05524cam a2200421Ii 4500 | ||
|---|---|---|---|
| 001 | 95752 | ||
| 003 | ES-MaUEC | ||
| 005 | 20230102112720.0 | ||
| 006 | m o d | ||
| 007 | cr cnu|||unuuu | ||
| 008 | 170405s2017 nyua ob 001 0 eng d | ||
| 020 |
_a3319520318 _q(electronic bk.) |
||
| 020 |
_a9783319520315 _q(electronic bk.) |
||
| 020 | _z3319520296 | ||
| 020 |
_z9783319520292 _q(print) |
||
| 040 |
_aN$T _cN$T _dN$T _dEBLCP _dGW5XE _dYDX _dOCLCF _dUAB _dMERER _dESU _dIOG _dOCLCQ _dNJR _dVT2 _dOTZ _dJG0 _dU3W _dES-MaUEC _bspa |
||
| 050 | 4 |
_aQP88.15 _bA357 2017 EB |
|
| 245 | 0 | 0 |
_aAdipose tissue biology _cMichael E. Symonds, editor. |
| 250 | _aSecond edition. | ||
| 264 | 1 |
_aNew York _bSpringer _c[2017] |
|
| 300 |
_a1 recurso en línea _bilustraciones |
||
| 336 |
_aTexto _btxt _2rdacontent |
||
| 337 |
_aelectrónico _bc _2rdamedia |
||
| 338 |
_arecurso electrónico _bcr _2rdacarrier |
||
| 500 |
_aSpringerLink _bSpringer Biomedical and Life Sciences eBooks 2017 English+International |
||
| 504 | _aIncluye referencias bibliográficas e índice | ||
| 505 | 0 | _aChapter 1: The Evolution of€Mammalian Adipose Tissues; 1.1 Introduction; 1.1.1 Comparative Perspectives on€Obesity and€Diabetes; 1.2 Storage Tissues; 1.2.1 Invertebrates; 1.2.2 Vertebrate Adipose Tissues; 1.2.3 Fish, Amphibians and€Reptiles; 1.3 White Adipose Tissue in€Mammals and€Birds; 1.3.1 Anatomical Distribution and€Site-Specific Properties; 1.3.2 Cellular Structure of€Adipose Tissue; 1.3.3 Structural Adipose Tissue; 1.4 Brown and€Beige Adipose Tissue; 1.4.1 Origins of€Thermogenic Mechanisms; 1.5 The Specificity of€Fatty Acids; 1.5.1 Structural Lipids. | |
| 505 | 8 | _a1.5.2 Storage Lipids as€Fuels1.5.3 Fatty Acid Sorting; 1.6 Paracrine Interactions with€Adipose Tissue; 1.6.1 The Immune System; 1.6.2 Perinodal Adipose Tissue Around Lymph Nodes; 1.6.3 Permeating Dendritic Cells; 1.6.4 Adipose Tissue in€Normal Immune Function; 1.6.5 Human Perinodal Adipose Tissue; 1.6.6 Paracrine Interactions with€Muscle; 1.6.7 Cardiac Adipose Tissues; 1.6.8 Perivascular Adipose Tissue; 1.7 Adipose Tissues for€Mammalian Habits and€Habitats; 1.7.1 Diet; 1.7.2 Controlled Heterothermy and€Thermogenesis; 1.7.3 Pregnancy and€Lactation. | |
| 505 | 8 | _a1.7.4 Primates and€the€Origins of€Human Obesity1.7.5 Rapid Adaptation to€Modern Diets and€Lifestyles; 1.8 Conclusions; References; Chapter 2: Adipocyte Progenitors from€Human Pluripotent Stem Cells; 2.1 Introduction; 2.2 Potential of€Human PSCs to€Generate Adipocytes; 2.3 Adipogenic Capacity of€hPSC-Derived Adipocyte Progenitors; 2.4 Developmental Origins of€Human Brown Adipocyte Progenitors; References; Chapter 3: Adipocyte Differentiation; 3.1 Introduction; 3.2 In Vitro Experimental Systems to Study Adipocyte Differentiation; 3.2.1 Preadipocyte Cell Lines. | |
| 505 | 8 | _a3.2.2 Mature Adipocyte-Derived Dedifferentiated Fat Cells3.2.3 Mesenchymal Stem Cells; 3.2.4 Adipose-Derived Stem Cells (ADSCs); 3.3 Stages of Adipocyte Differentiation; 3.4 Nuclear Regulation of Adipocyte Differentiation; 3.4.1 Transcriptional Regulation of Adipocyte Differentiation; 3.4.2 Transcriptional Cofactors in Adipogenesis; 3.5 Extranuclear Regulation of Adipocyte Differentiation; 3.5.1 Adipogenic Factors; 3.5.2 Antiadipogenic Factors; 3.5.3 Other Players in the Regulation of Adipogenesis; 3.5.3.1 Epigenetic Factors in Adipogenesis; 3.5.3.2 The Role of miRNAs in Adipogenesis. | |
| 505 | 8 | _a3.5.3.3 Chronobiology in Adipogenesis3.6 Future Perspectives; References; Chapter 4: Brown Adipose Tissue; 4.1 Biological Significance of€Brown Adipose Tissue; 4.2 Anatomy and€Innervation; 4.3 Molecular Mechanism of€Thermogenesis in€Brown Adipose Tissue; 4.3.1 Mitochondrial Bioenergetics; 4.3.2 UCP1 as€a€Catalyst of€Uncoupled Respiration in€Brown Adipocytes; 4.3.3 Mode of€UCP1 Action; 4.4 Activation of€Brown Adipose Tissue; 4.4.1 The Central POA-DMH-rPAa Axis Controls Acute Brown Adipose Tissue Thermogenesis; 4.4.2 Neuroendocrine Stimulation of€Diet-Induced BAT Thermogenesis. | |
| 520 | 3 | _aThe past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tissue this still has had limited impact on the on-going obesity epidemic across a majority of countries in the world. This book brings together many leading experts in the field to provide an up to date and comprehensive review of the key aspects of adipose tissue. It therefore includes chapters on evolution, development and inflammation together with a detailed review of brown and beige adipose tissue biology and their potential significance in preventing or combating obesity. These chapters are complemented by those on genetics and gender influences, together with nutrition through the life cycle. Ultimately the book provides an overview of the complexities of adipose tissue biology and the continuing challenge to combat obesity in the 21st century. | |
| 650 | 7 |
_9667182 _aTejido adiposo _2fast _0(OCoLC)fst00796650 _0 |
|
| 700 | 1 |
_aSymonds, Michael E., _d1960- _eeditor literario |
|
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-52031-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 988 | _aEBOOK, asignarmaterias, EBSPRINGER_2017C | ||
| 998 |
_b02/2018 _dz _e- _zSI |
||
| 999 |
_c95752 _d95752 _x1 |
||