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020 _a3319530828
_q(electronic bk.)
020 _a9783319530826
_q(electronic bk.)
020 _z331953081X
020 _z9783319530819
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050 4 _aRC268.4
_bM654 2017 EB
245 0 0 _aMolecular oncology :
_bunderlying mechanisms and translational advancements
_cAmmad Ahmad Farooqi, Muhammad Ismail, editors.
264 1 _aCham, Switzerland
_bSpringer
_c2017.
300 _a1 recurso en línea (x, 302 páginas)
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aIncluye índice
500 _aSpringerLink
_bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505 0 _aMicrotubule targeting agents in cancer therapy: Elucidating the underlying molecular mechanisms -- Adenosine signaling pathways as potential therapeutic targets in cancer disease -- Anticancer activities of Hippophae rhamnoides: Journey from Benchtop to the Bedside -- Emerging role of ncRNAs in cancer biology: techniques for diagnostic monitoring and potential ncRNA-based therapies -- Clinical and translational research on the pathophysiology of several ocular tumors types -- Exosomes and cancer: from diagnosis to therapy -- Blood-based Cancer Detection: Towards Solving Diagnostic Puzzle -- Non-coding RNAs, Critical Therapy Targets against Cancer -- Detection of Virus-caused Cancer in Publicly Available Next Generation Sequencing Data -- TRAIL mediated signaling in prostate cancer -- Index.
520 3 _aCancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasingly sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer, and it is now known that intra-tumor genetic heterogeneity, cellular plasticity, dysregulation of spatio-temporally controlled signaling cascades, and loss of apoptosis are contributory in cancer development, progression and the development of resistance against different therapeutics. It is becoming progressively more understandable that earlier detection of pre-existing or emerging resistance against different therapeutics may prove to be helpful in personalizing the use of targeted cancer therapy. Despite the fact that there is a continuously increasing list of books, being guest edited by researchers, books on the subject are often composed of invited reviews without proper sequence and continuity and designed for a particular readership. This book progressively shifts and guides the readers from basic underlying mechanisms to translational approaches to treat cancer.
650 7 _aCancer
_xMolecular aspects.
_2fast
_0(OCoLC)fst00845397
_9139308
_0comprobar BNE19900970859
700 1 _aFarooqi, Ammad Ahmad,
_eeditor literario
700 1 _aIsmail, Muhammad,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-53082-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017C
998 _b02/2018
_dz
_e-
_zSI
999 _c95716
_d95716
_x1