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020 _a3662539942
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020 _a9783662539941
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020 _z3662539926
020 _z9783662539927
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050 4 _aRK322
_b2017 EB
245 0 0 _aOrofacial pain biomarkers
_cJean-Paul Goulet, Ana Miriam Velly, editors.
264 1 _aBerlin, Germany
_bSpringer
_c2017.
300 _a1 recurso en línea (x, 155 páginas)
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aIncluye índice
500 _aSpringerLink
505 0 _aBackground: Chronic Orofacial Pain Conditions -- Neurobiologic Mechanisms of Chronic Orofacial Pain -- Biomarkers -- Role for Diagnosis, Treatment and Prognosis of Orofacial Pain -- Methodology: Saliva and Serum Biomarkers -- The Search for Pain Biomarkers -- Orofacial Pain Biomarkers: Contribution of Animal Studies -- Masticatory Muscle Pain Biomarkers and Biochemical Fingerprint of Myofascial Trigger Points -- Temporomandibular Joint Pain Biomarkers -- Genetic Biomarkers and Temporomandibular Pain Disorders -- Neurophysiologic and Neuropathologic Biomarkers in Neuropathic Face Pain -- Biomarkers of Autonomic System Involvement in Trigeminal Face Pain -- Immune System and the Modulation of Cytokines Biomarkers -- New Perspectives: Future Studies, Limitation, Clinical Implication -- Conclusion.
520 3 _aThis book provides up-to-date information on all aspects of orofacial pain biomarkers. It opens by presenting background information on clinical phenotypes and the neurobiological substrates underlying chronic orofacial pain and by explaining the potential role of biomarkers in the diagnosis, prognostic evaluation, and treatment of orofacial pain. The main section of the book examines the contribution of human and animal studies to the field of biomarkers for orofacial pain and discusses biomarkers for masticatory muscle pain, temporomandibular joint pain, neuropathic face pain, and autonomic nervous system involvement in trigeminal facial pain. The potential impacts of the immune system on orofacial pain biomarkers and candidate gene phenotypes with possible links to chronic orofacial pain conditions are also addressed, and differences and similarities between saliva and serum biomarkers for pain are explained as well. The final section covers research-related issues in assessment methods and statistical analyses used in evaluating biomarkers, identifies future challenges and suggests new directions in the field.
588 0 _aOnline resource; title from PDF title page (SpringerLink, viewed March 30, 2017).
650 7 _2embne
_9162337
_aDolor orofacial
700 1 _aGoulet, Jean-Paul,
_eeditor literario
700 1 _aVelly, Ana Miriam,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-662-53994-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2018
_dz
_e-
_zSI