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020 _a3319438042
020 _a3319438069
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020 _a9783319438047
020 _a9783319438061
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020 _z9783319438047
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050 4 _aRA1250
_b.T695 2017 EB
245 0 0 _aToxicology of herbal products
_cOlavi Pelkonen, Pierre Duez, Pia Maarit Vuorela, Heikki Vuorela, editors.
264 1 _aCham, Switzerland
_bSpringer
_c2017.
300 _a1 recurso en línea (xvi, 479 páginas)
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aIncluye índice
500 _aSpringerLink
504 _aIncluye referencias bibliográficas e índice
505 0 _aPreface; About the Editors; Contents; Contributors; Chapter 1: Toxicity of Herbal Medicines: From Past to Present to Future; Introduction; Herbal Medicines and Human Beings; Definitions; Time Periods in the Toxicity of Herbal Medicines; Scientific Progress and the Development of Subdisciplines; Development of Regulation Related to the Toxicity of Herbal Medicines; Global Diversity and Future Challenges; References; Chapter 2: History and Current Status of Herbal Medicines; History and Current Status of Herbal Medicines and Herbal Medicinal Products.
505 8 _aComplexes and Colloidal Dispersions Solubilization by Polar Matrix Constituents; Stabilization; Pharmacokinetic Synergy; Chemometrics for Quality Control of Finished Herbal Medicines; Quality Control by Only One or a Few Constituents; Quality Control by Chemical Fingerprints; Chromatographic Techniques; Spectroscopic and Hyphenated Techniques; Chemometric Methods; Examples for the Chemometric Analysis of Chemical Fingerprints; Future Challenges; Conclusions; References; Chapter 4: Toxicokinetics of Herbal Products.
505 8 _aEarly Evidence of Use of Herbal Medicine Neanderthal Period; Neolithic Period; Pre-Christian Period; First Century to the Middle Ages; Non-human Use of Herbal Medicine; Herbal Medicine to Pharmaceuticals; Apothecaries: The Foundation of Pharmaceutical Companies; Plants as the Source of Early Pharmaceuticals; Distribution of Medicinal Plant Species; Source of Herbal Material; Wild Harvest; Cultivation; Wild Harvest vs. Cultivation; The Current Position of Herbal Medicine and Traditional Herbal Medicine; Global Use; New and Emerging Uses; Herbal Medicine Industries.
505 8 _aFactors Affecting the Chemical Composition of an Herbal Preparation Plant Growth and Collection; Drying; Stability During Storage; Specific Processing; Extraction; Relevance of Chemical Adulterations; Herbal Material and Products: Chemical Composition; Classification of Plant Constituents; Unspecific Matrix Constituents; Plant Secondary Metabolites; Therapeutic Relevance; Actives Directly Related to Quality; Actives and Co-effectors Indirectly Related to Quality; The Example of St. John's Wort; Phenolics as Solubilizers; Saponins as Solubilizers.
505 8 _aPharmaceutical Companies Phytopharmaceutical Companies; Nutraceutical Companies; References; Chapter 3: Composition and Quality Control of Herbal Medicines; Introduction; Guidelines on Production of Quality Herbal Material and Herbal Medicinal Products; Good Agricultural and Collection Practices (GACP); Good Manufacturing Practices (GMP); Pharmacopoeias and Herbal Medicinal Plants; Herbal Monographs; EU Directive 2004/24/EC; Quality of Herbal Material and Herbal Medicinal Products; Naming of Plants and Herbal Materials; Plant Species; Herbal Products.
520 3 _aThis volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities. With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.
588 0 _aOnline resource; title from PDF title page (SpringerLink, viewed March 22, 2017).
988 _aEBOOK, EBSPRINGER_2017C
650 7 _2embne
_9671715
_aPlantas venenosas
700 1 _aDuez, Pierre,
_eeditor literario
700 1 _aPelkonen, R. O.
_q(R. Olavi),
_eeditor literario
700 1 _aVuorela, Heikki,
_eeditor literario
700 1 _aVuorela, Pia Maarit,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-43806-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2018
_dz
_e-
_zSI