| 000 | 05499cam a2200469Ii 4500 | ||
|---|---|---|---|
| 988 | _aSpringer_Medicine_2017 | ||
| 999 |
_c95527 _d95527 _x1 |
||
| 001 | 95527 | ||
| 003 | ES-MaUEC | ||
| 005 | 20230102112708.0 | ||
| 006 | m o d | ||
| 007 | cr cnu|||unuuu | ||
| 008 | 170308s2017 gw a ob 001 0 eng d | ||
| 020 |
_a3662537753 _q(electronic bk.) |
||
| 020 |
_a9783662537756 _q(electronic bk.) |
||
| 020 | _z3662537737 | ||
| 020 | _z9783662537732 | ||
| 040 |
_aN$T _cN$T _dN$T _dOCLCO _dEBLCP _dGW5XE _dIDEBK _dYDX _dUAB _dIOG _dCOO _dAZU _dUPM _dMERER _dESU _dOCLCQ _dJBG _dIAD _dICW _dICN _dOTZ _dOCLCQ _dOHI _dOCLCQ _dU3W _dES-MaUEC _bspa |
||
| 050 | 4 |
_aRC280.G47 _b2017 EB |
|
| 245 | 0 | 0 |
_aPathology and biology of human germ cell tumors _cFrancisco F. Nogales, Rafael E. Jimenez, editors. |
| 264 | 1 |
_aBerlin _bSpringer _c[2017] |
|
| 264 | 4 | _c2017 | |
| 300 |
_a1 recurso en línea _bilustraciones |
||
| 336 |
_aTexto _btxt _2rdacontent |
||
| 337 |
_aelectrónico _bc _2rdamedia |
||
| 338 |
_arecurso electrónico _bcr _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 500 | _aSpringerLink | ||
| 504 | _aIncluye referencias bibliográficas e índice | ||
| 505 | 0 | _aPreface; References; Contents; Contributors; 1: Germ Cell Tumors: Classifications, Definitions, and Terminology; 1.1 Introduction; 1.2 Classification of Testicular Germ Cell Tumors; 1.3 Classification of Ovarian Germ Cell Tumors; 1.4 Definitions and Terminology of Testicular and Ovarian Germ Cell Tumors; References; 2: The Epidemiology of Malignant Germ Cell Tumors: The EUROCARE Study; 2.1 Introduction; 2.2 Materials; 2.3 Incidence; 2.4 Incidence Trends of Gonadal and Extragonadal Germ Cell Tumors; 2.5 Survival; References. | |
| 505 | 8 | _a3.5.1 Type I GCT General; 3.5.1.1 Developmental Potential; 3.5.1.2 Epidemiology; 3.5.1.3 Anatomical Distribution; 3.5.1.4 (Cyto)Genetics; 3.5.1.5 Epigenetics, including GI; 3.5.1.6 Animal Models and Pathogenesis; 3.5.1.7 Summary of the Pathogenesis of Type I GCT; 3.5.2 Site-Specific Aspects of Type I GCT; 3.5.2.1 Sacral Region; 3.5.2.2 Retroperitoneum; 3.5.2.3 Stomach; 3.5.2.4 Mediastinum; 3.5.2.5 Heart; 3.5.2.6 Head and Neck; 3.5.2.7 Brain; 3.5.2.8 Testis; 3.5.2.9 Ovary; 3.5.3 Type I GCT Beyond Infancy; 3.6 Type II GCT; 3.6.1 Type II GCT General. | |
| 505 | 8 | _a3.6.1.1 Developmental Potential; 3.6.1.2 Epidemiology; 3.6.1.3 Anatomical Distribution; 3.6.1.4 (Cyto)Genetics; 3.6.1.5 Epigenetics: Including GI and miRNAs; 3.6.1.6 Sensitivity/Resistance/Residual Teratoma/Further Progression; 3.6.1.7 Animal Models and Cell Lines; 3.6.2 Specific Aspects of Pathogenesis per Anatomical Site; 3.6.2.1 Dysgenetic Gonad; 3.6.2.2 Testis; 3.6.2.3 Ovary; 3.6.2.4 Mediastinum; 3.6.2.5 Central Nervous System; 3.6.3 Type II GCT Before Puberty; 3.7 Type III GCT; 3.7.1 Developmental Potential; 3.7.2 Epidemiology/Risk Factors; 3.7.3 Anatomical Distribution. | |
| 505 | 8 | _a3.7.4 (Cyto)Genetics; 3.7.5 Epigenetics Including GI; 3.7.6 Pathogenesis and Animal Models; 3.8 Type IV GCT; 3.8.1 Developmental Potential; 3.8.2 Epidemiology/Risk Factors; 3.8.3 Anatomical Distribution; 3.8.4 (Cyto)Genetics; 3.8.5 Epigenetics Including GI; 3.8.6 Pathogenesis and Animal Models; 3.9 Type V GCT; 3.9.1 Developmental Potential; 3.9.2 Epidemiology/Risk Factors; 3.9.3 Anatomical Distribution; 3.9.4 (Cyto)Genetics/Epigenetics Including GI; 3.9.5 Pathogenesis and Animal Models; 3.10 Type VI GCT; 3.10.1 Definition. | |
| 505 | 8 | _a3: Germ Cell Tumors from a Developmental Perspective: Cells of Origin, Pathogenesis, and Molecular Biology (Emerging Patterns); 3.1 Introduction; 3.2 Developmental States of Early Embryonic Cells; 3.2.1 Restriction Versus Maintaining Developmental Potential; 3.2.2 OCT4: Key Protein in Pluripotency; 3.2.3 Specification and Maintenance of the Germline; 3.2.4 Plasticity of Pluripotent States; 3.3 Developmental Potential of Germ Cell Tumors; 3.4 Type 0 GCT; 3.4.1 Developmental Potential and Incidence; 3.4.2 Anatomical Distribution; 3.4.3 Genetics and Pathogenesis; 3.5 Type I GCT. | |
| 520 | 3 | _aThis book provides, for the first time, a detailed, up-to-date, holistic approach to the pathology and biology of germ cell tumors. The main focus is the complex histopathology of these tumors, but special considerations are also given to their morphologic variations in relation to age, gender and organ. Critical updates are provided on terminology and classification; the discussion of biology and pathogenesis includes references to many molecular genetic and immunohistochemical findings from recent stem cell research. Individual chapters are devoted to germ cell tumors at different anatomic locations, including not only the ovaries and testes but also the mediastinum and central nervous system, and pediatric tumors. All of the contributing authors are opinion leaders from universities of excellence in Europe and the United States. This monograph will be of wide interest to practitioners and researchers in many fields of medicine, including pathology, gynecology, urology, and pediatrics, as well as stem cell scientists. | |
| 588 | 0 | _aVendor-supplied metadata. | |
| 650 | 7 |
_2embne _aAparato urinario _9144856 |
|
| 700 | 1 |
_aJimenez, Rafael E., _eeditor literario |
|
| 700 | 1 |
_aNogales Ortiz, Francisco, _eeditor literario |
|
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-662-53775-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 942 |
_2lcc _cLE |
||
| 998 |
_b02/2018 _dz _e- _zSI |
||