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050 4 _aRC78.7.C65
_bL387 2017 EB
100 1 _aLaurent, Sophie,
_eautor
245 1 0 _aMRI Contrast Agents :
_bFrom Molecules to Particles
_cby Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid, Robert N. Muller, Luce Vander Elst.
264 1 _aSingapore
_bSpringer
_c2017
300 _a1 recurso en línea (VII, 125 páginas)
_bilustraciones (algunas a color)
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 0 _aSpringerBriefs in Applied Sciences and Technology
_x2191-530X
500 _aSpringerLink
_bSpringer Engineering eBooks 2017 English+International
504 _aIncluye referencias bibliográficas
505 0 _aNanomaterials in medicine -- Magnetic properties (diamagnetism, paramagnetism, ferromagnetism, ferrimagnetism, antiferromagnetism, superparamagnetism) -- Imaging probes -- Magnetic resonance imaging (MRI) -- Bases of MRI -- MRI contrast agents -- Paramagnetic gadolinium complexes -- Superparamagnetic iron oxide nanoparticles -- Synthesis of magnetic nanoparticles -- Stabilization of magnetic nanoparticles -- Physico-chemical characterization of nanoparticles -- MRI applications -- Conclusions.
520 3 _aThis book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.
650 7 _9143820
_aIngeniería biomédica
_2fast
_0(OCoLC)fst00832568
_0
700 1 _aBelaid, Sarah,
_eautor
700 1 _aBoutry, Sébastien,
_eautor
700 1 _aHenoumont, Céline,
_eautor
700 1 _aLipani, Estelle,
_eautor
700 1 _aMuller, Robert N.,
_eautor
700 1 _aStanicki, Dimitri,
_eautor
700 1 _aVander Elst, Luce,
_eautor
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-981-10-2529-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017C
998 _b02/2018
_dz
_e-
_zSI
999 _c95513
_d95513
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