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988			_aSpringer_Medicine_2017
988			_aEbook_one2one
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020			_a9789811032929 _q(electronic bk.)
020			_a9811032920 _q(electronic bk.)
020			_z9789811032912 _q(hardcover ; _qalk. paper)
020			_z9811032912 _q(hardcover ; _qalk. paper)
040			_aN$T _cN$T _dGW5XE _dIDEBK _dEBLCP _dN$T _dYDX _dMMU _dOCLCO _dNJR _dIOG _dCOO _dAZU _dUPM _dOCLCO _dUAB _dOCLCO _dMERER _dESU _dOCLCQ _dOCLCO _dJBG _dIAD _dOCLCO _dICW _dOCLCO _dICN _dILO _dOCLCO _dOTZ _dVT2 _dOCLCQ _dOCLCO _dU3W _dES-MaUEC _bspa
050		4	_aQP321 _b2017 EB
245	0	4	_aThe plasticity of skeletal muscle : _bfrom molecular mechanism to clinical applications _cKunihiro Sakuma, editor.
264		1	_aSingapore _bSpringer _c[2017]
264		4	_c2017
300			_a1 recurso en línea (ix, 292 páginas) _bilustraciones (algunas a color)
336			_astill image _bsti _2rdacontent
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF _2rda
500			_aSpringerLink
504			_aIncluye referencias bibliográficas
505	0		_aPluripotent stem cells and skeletal muscle differentiation: challenges and immediate applications -- Role of the ubiquitin-proteasome pathway in skeletal muscle -- Stem cell therapy in muscle degeneration -- The autophagy-dependent signaling in skeletal muscle -- Cytokines in skeletal muscle growth and decay -- The role of ribosome biogenesis in skeletal muscle hypertrophy -- Comprehensive approach to sarcopenia and cachexia treatment -- The role and regulation of PGC-1[alpha] and PGC-1[beta] in skeletal muscle adaptation -- Characteristics of skeletal muscle as a secretory organ -- Biological role of TRPC1 in myogenesis, regeneration, and disease -- ROS and nNOS in the regulation of disuse-induced skeletal muscle atrophy -- Participation of AMPK in the control of skeletal muscle mass -- Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy and related muscle conditions.
520	3		_aThis book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis. The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered. It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.
588	0		_aOnline resource; title from electronic title page (ProQuest Ebook Central, viewed April 6, 2017).
650		7	_2embne _aMúsculos _9138568
700	1		_aSakuma, Kunihiro, _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-981-10-3292-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI