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008			170302s2017 sz o 001 0 eng d
020			_a331944820X _q(electronic bk.)
020			_a9783319448206 _q(electronic bk.)
020			_z3319448196
020			_z9783319448190 _q(print)
040			_aN$T _cN$T _dIDEBK _dEBLCP _dGW5XE _dDKU _dYDX _dN$T _dOCLCF _dCOO _dIOG _dAZU _dUPM _dMERER _dESU _dZ5A _dOCLCQ _dJBG _dIAD _dICW _dICN _dOTZ _dUV1 _dOCLCQ _dU3W _dES-MaUEC _bspa
050		4	_aQL964 _b.S546 2017 EB
245	0	0	_aSignaling-mediated control of cell division : _bfrom oogenesis to oocyte-to-embryo development _cSwathi Arur, editor.
264		1	_aCham, Switzerland _bSpringer _c2017.
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	0		_aResults and problems in cell differentiation _vvolume 59
500			_aIncluye índice
500			_aSpringerLink _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
505	0		_aChapter 1. Role of chromatin modifications in germline stem cell differentiation -- Chapter 2. Regulation of the balance between proliferation and differentiation in germline stem cells -- Chapter 3. Control of germ line stem cell lineages by diet and physiology -- Chapter 4. Signal-mediated regulation of meiotic prophase I during oogenesis -- Chapter 5. Prophase I: preparing chromosomes for segregation in the developing oocyte -- Chapter 6. Translational control of germ cell decisions -- Chapter 7. Prostagladin signaling from oocyte to sperm -- Chapter 8. Cell fate maintenance and reprogramming during the oocyte-to-embryo transition? -- Chapter 9. Cell cycle regulation in oocytes -- Chapter 10. Oocyte activation and fertilization: crucial sperm and oocyte factors.
520	3		_aThis volume covers the current knowledge base on the role of signaling and environmental pathways that control the normal development of germline stem cells, meiotic progression of oocytes, events of oocyte maturation and fertilization, and the birth of an embryo. Germ cells are uniquely poised to sustain life across generations through the fusion of oocyte and sperm. Because of the central importance of germ cells to life, much work has been dedicated to obtaining a clear understanding of the molecular and signaling events that control their formation and maintenance. Germ cells are set aside from somatic cells in the embryo and go through specialized meiotic cell cycles as the animal matures. These cell cycles are interspersed with long periods of arrest. In human females, meiosis I is initiated in the fetus. At birth, oocytes are arrested in meiosis I; after puberty, every month an oocyte initiates meiosis II ℓ́ℓ ovulation. Upon sperm availability these cells are fertilized, generate an embryo, and the cycle-of-life continues. During meiotic I progression and arrest, the fitness of oocytes and their progeny are likely influenced by environmental cues and signaling pathways. A lot of recent work has focused on understanding the mechanisms that regulate oocyte fitness and quality in humans and vertebrates. Much of our understanding on the events of meiosis I and germline stem cell populations comes from work in invertebrates, wherein the germline stem cells produce oocytes continuously through adult development. In both inverbrates and vertebrates nutritional and signaling pathways control the regulation of stem cells in such a manner so as to couple production of gametes with the nutritional availability. Additionally, mature oocytes arrest both in meiosis I and meiosis II, and signaling and nutritional pathways have been shown to regulate their formation, and maintenance, such that despite long periods of arrest, the oocyte quality is assured and errors in chromosome segregation and varied cytoplasmic events are minimal.
650		7	_aCélulas vegetales _0(OCoLC)fst00850288 _0 _2embne _9146302
700	1		_aArur, Swathi, _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-44820-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017C
998			_b02/2018 _dz _e- _zSI
999			_c95485 _d95485 _x1