000			05592cam a2200421Ii 4500
001			95408
003			ES-MaUEC
005			20230102112702.0
006			m o d
007			cr |||||||||||
008			170218t20172017sz a ob 001 0 eng d
020			_a3319500449 _q(electronic bk.)
020			_a9783319500447 _q(electronic bk.)
020			_z3319500430 _q(print)
020			_z9783319500430 _q(print)
035			_a(OCoLC)973181706 _z(OCoLC)973086296 _z(OCoLC)973302220 _z(OCoLC)973379379 _z(OCoLC)973523868 _z(OCoLC)973764175 _z(OCoLC)973806913
040			_aEBLCP _cEBLCP _dOCLCO _dGW5XE _dN$T _dIDEBK _dMMU _dOCLCO _dYDX _dOCLCO _dUAB _dIOG _dOCLCO _dMERER _dESU _dZ5A _dOCLCO _dJBG _dIAD _dOCLCO _dICW _dOCLCO _dICN _dOCLCQ _dOCLCO _dOTZ _dOCLCQ _dMERUC _dTFH _dOCLCO _dU3W _dOCLCO _dOCLCA _dES-MaUEC _bspa
050		4	_aQH581.2 _bS866 2017 EB
245	0	0	_aSUMO regulation of cellular processes _cVan G. Wilson, editor.
250			_aSecond edition.
264		1	_aCham, Switzerland _bSpringer _c[2017]
264		4	_c2017
300			_a1 recurso en línea (viii, 415 páginas) _bilustraciones
336			_astill image _bsti _2rdacontent
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in experimental medicine and biology _x2214-8019 _vvolume 963
500			_aSpringerLink _bSpringer Biomedical and Life Sciences eBooks 2017 English+International
504			_aIncluye referencias bibliográficas e índice
505	0		_aIntroduction to Sumoylation / Van G. Wilson -- Molecular function. Roles of sumoylation in mRNA processing and metabolism / Patricia Richard, Vasupradha Vethantham, James L. Manley -- SUMO and chromatin remodeling / David Wotton, Lucy F. Pemberton, Jacqueline Merrill-Schools -- Functions of SUMO in the maintenance of genome stability / Nicola Zilio, Karolin Eifler-Olivi, Helle D. Ulrich -- Regulation of cellular processes by SUMO: understudied topics / Jorrit M. Enserink -- The molecular interface between the SUMO and ubiquitin systems / Jeff L. Staudinger -- SUMO and nucleocytoplasmic transport / Christopher Ptak, Richard W. Wozniak -- SUMO modification of ion channels / Mark Benson, Jorge A. Iñiguez-lluhí, Jeffrey Martens -- The roles of SUMO in metabolic regulation / Elena Kamynina, Patrick J. Stover -- Cell growth regulation. The SUMO pathway in mitosis / Debaditya Mukhopadhyay, Mary Dasso -- Wrestling with chromosomes: the roles of SUMO during meiosis / Amanda C. Nottke, Hyun-Min Kim, Monica P. Colaiácovo -- Sumoylation in development and differentiation / Adeline F. Deyrieux, Van G. Wilson -- The role of sumoylation in senescence / Lyndee L. Scurr, Sebastian Haferkamp, Helen Rizos -- Regulation of plant cellular and organismal development by SUMO / Nabil Elrouby -- SUMO in drosophila development / Joseph Cao, Albert J. Courey -- Diseases. Sumoylation: implications for neurodegenerative diseases / Dina B. Anderson, Camila A. Zanella, Jeremy M. Henley, Helena Cimarosti -- Sumoylation and its contribution to cancer / Jason S. Lee, Hee June Choi, Sung Hee Baek -- Sumoylation modulates the susceptibility to type 1 diabetes / Jing Zhang, Zhishui Chen, Zhiguang Zhou, Ping Yang, Cong-Yi Wang -- Sumoylation in craniofacial disorders / Erwin Pauws, Philip Stanier -- Coordination of cellular localization-dependent effects of sumoylation in regulating cardiovascular and neurological diseases / Jun-ichi Abe, Uday G. Sandhu, Nguyet Minh Hoang, Manoj Thangam [and others] -- Sumoylation as an integral mechanism in bacterial infection and disease progression / Chittur V. Srikanth, Smriti Verma.
520	3		_a"This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule. Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins. The book is divided into three themed parts: Molecular Functions (I), Cell Growth Regulation (II), and Diseases (III). Parts I and II focus on the contribution of sumoylation to cellular activities in both the nuclear and cytoplasmic compartments. The nuclear activities covered include nucleic acid metabolism (both RNA and DNA), chromosome structure and replication, and nucleocytoplasmic transport. Cytoplasmic processes presented include regulation of membrane ion channels, general metabolism, and apoptotic signalling. Topics in Part III include the role of sumoylation in developmental abnormalities (craniofacial and cardiovascular), diabetes, neurodegenerative diseases, cancer, and infections with viruses and bacteria. Each of the corresponding chapter authors is an active researcher who has made significant contributions to understanding sumoylation. This second edition provides updates and revisions to most of the original chapters plus adds six new chapters to address important developing areas of sumoylation research"--Publisher's description.
650		7	_aCélulas vegetales _0(OCoLC)fst01072761 _0 _2embne _9146302
700	1		_aWilson, Van Gene.
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-50044-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aEBOOK, asignarmaterias, EBSPRINGER_2017B
998			_b02/2018 _dz _e- _zSI
999			_c95408 _d95408 _x1