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020 _a3319506935
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020 _a9783319506937
_q(electronic bk.)
020 _z3319506927
020 _z9783319506920
035 _a(OCoLC)972331022
_z(OCoLC)972591270
_z(OCoLC)972772706
_z(OCoLC)972944769
_z(OCoLC)973132082
_z(OCoLC)973302960
_z(OCoLC)973382730
_z(OCoLC)973520291
_z(OCoLC)973771460
_z(OCoLC)981888700
_z(OCoLC)1005757486
_z(OCoLC)1011906339
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050 4 _aQP752.F35
_bF744 2017 EB
245 0 0 _aFree fatty acid receptors
_cGraeme Milligan, Ikuo Kimura, editors.
264 1 _aCham, Switzerland
_bSpringer
_c[2017]
264 4 _c2017
300 _a1 recurso en línea (viii, 254 páginas)
_bilustraciones (algunas a color)
336 _astill image
_bsti
_2rdacontent
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 0 _aHandbook of experimental pharmacology
_x1865-0325
_vvolume 236
500 _aSpringerLink
_bSpringer Biomedical and Life Sciences eBooks 2017 English+International
504 _aIncluye referencias bibliográficas e índice
505 0 _aLigands at free fatty acid receptor 1 (GPR40) / Takafumi Hara -- Ligands at the free fatty acid receptors 2/3 (GPR43/GPR41) / Graeme Milligan, Daniele Bolognini, Eugenia Sergeev -- Pharmacological tool compounds for the free fatty acid receptor 4 (FFA4/GPR120) / Steffen V.F. Hansen, Trond Ulven -- Application of GPCR structures for modelling of free fatty acid receptors / Irina G. Tikhonova -- Using biosensors to study free fatty acid receptor pharmacology and function / Brian D. Hudson -- Key questions for translation of FFA receptors: from pharmacology to medicines / Arthur T. Suckow, Celia P. Briscoe -- Polymorphic variation in FFA receptors: functions and consequences / Atsuhiko Ichimura -- The role and future of FFA1 as a therapeutic target / Julien Ghislain, Vincent Poitout -- Gut hormone regulation and secretion via FFA1 and FFA4 / Fiona M. Gribble, Eleftheria Diakogiannaki, Frank Reimann -- FFA2 and FFA3 in metabolic regulation / Cong Tang, Stefan Offermanns -- Anti-inflammatory and insulin-sensitizing effects of free fatty acid receptors / Junki Miyamoto, Mayu Kasubuchi, Akira Nakajima, Ikuo Kimura -- Free fatty acid receptors and cancer: from nutrition to pharmacology / Mandi M. Hopkins, Kathryn E. Meier.
520 3 _a"This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands"--Publisher's description.
650 7 _aBioquímica clínica
_2embne
_0(OCoLC)fst00864329
_0
_9149316
700 1 _aKimura, Ikuo,
_eeditor literario
700 1 _aMilligan, Graeme,
_eeditor literario
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-50693-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017B
998 _b02/2018
_dz
_e-
_zSI
999 _c95372
_d95372
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