000 06091cam a2200445Ii 4500
001 95371
003 ES-MaUEC
005 20230102112700.0
006 m o d
007 cr cnu|||unuuu
008 170213s2017 sz ob 000 0 eng d
020 _a3319477633
_q(electronic bk.)
020 _a9783319477633
_q(electronic bk.)
020 _z3319477617
020 _z9783319477619
_q(print)
035 _a(OCoLC)972331019
_z(OCoLC)972605314
_z(OCoLC)972869302
_z(OCoLC)972998157
_z(OCoLC)973003135
_z(OCoLC)973158091
_z(OCoLC)973189782
_z(OCoLC)973314652
_z(OCoLC)973368887
_z(OCoLC)981816787
_z(OCoLC)1005829681
_z(OCoLC)1011902673
040 _aN$T
_cN$T
_dGW5XE
_dN$T
_dYDX
_dEBLCP
_dIDEBK
_dOCLCF
_dNJR
_dUAB
_dCCO
_dCOO
_dIOG
_dAZU
_dUWO
_dVT2
_dUPM
_dESU
_dZ5A
_dJBG
_dIAD
_dICW
_dICN
_dOTZ
_dOCLCQ
_dU3W
_dES-MaUEC
_bspa
050 4 _aQH588.S83
_bP385 2017 EB
100 1 _aPavlovic, Mirjana
_q(Mirjana D.),
_eautor
245 1 0 _aAnimal and plant stem cells :
_bconcepts, propagation and engineering
_cMirjana Pavlović, Ksenija Radotić.
264 1 _aCham, Switzerland
_bSpringer
_c2017
300 _a1 recurso en línea
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aSpringerLink
_bSpringer Engineering eBooks 2017 English+International
504 _aIncluye referencias bibliográficas
505 0 _aPreface; Acknowledgements; Contents; Abstract; 1 Introduction; References; Bioengineering and Animal Stem Cells; 2 Current Status and Perspectives in Stem Cell Research: The Concept of Normal Stem (NSC) and Cancer Stem Cell (CSC); Abstract; 2.1 Introduction; 2.2 Stemness, Migration, Circulation, and Seeding; 2.3 Mobilization; 2.4 Similarities and Differences Between Embryonic and Adult Stem Cells; 2.5 Similarities and Differences Between Normal and Cancer Stem Cell; 2.6 Resume Based upon Similarities and Differences Between NSCs and CSCs.
505 8 _a2.7 What and Which Molecular Markers of CSCs We Know Today?2.8 Isolation of CSCs Using Magnetic Beads; 2.9 Theories of Origin of CSCs; 2.10 Current Tests for Determination of the Presence of CSCs; 2.11 Sorting and Isolation of CTC Using the Method of Magnetic Levitation; 2.12 The Emergence/Origin and Development of CSC: Mechanisms; 2.13 Aberrant Methylation; 2.14 What Do We Need to Do with the Sum of Information?; 2.15 How Was the Concept of CSC Therapy Designed?; References; 3 Essential Characteristics of Stem Cells: Self-renewal, and Plasticity; Abstract; 3.1 The Nature of Stem Cells.
505 8 _a3.2 Self-renewal and Its Significance for Stem Cells3.3 Plasticity/Pluripotency of Animal Stem Cells and Its Mechanisms; 3.4 Other Features of Significance; References; 4 Stem Cell Sources and Types of Animal Stem Cells; Abstract; 4.1 Introduction; 4.2 Embryonic SCs (ES or ESC); 4.3 Fetal Stem Cells (FSC); 4.4 Bone Marrow and Other Adult Stem Cells Sources; References; 5 Stemness and Stem Cell Markers; Abstract; 5.1 Introduction; 5.2 Human Embryonic Stem Cell Markers and Pluripotency; 5.3 Fetal Stem Cell Markers; 5.4 Cord Blood Stem Cell Markers; 5.5 Placental Stem Cell Markers.
505 8 _a5.6 Adult Stem Cell MarkersReferences; 6 Stem Cell Signaling Molecules and Pathways; Abstract; 6.1 Introduction; 6.2 ESC-Wnt Signaling; 6.2.1 Significant Discoveries in Wnt; 6.3 Notch Signaling; 6.4 The Human Hedgehog Signaling; 6.5 TGF-Beta Signaling; 6.6 Signaling Mechanisms in Adult Human Cells (HSC and MSC); 6.7 Pathways in Adult HSC; 6.8 Pathways in Adult Mesenchymal Stem Cells; 6.9 Pathways in CSC; 6.10 The JAK (Janus Kinase)/STAT3 (Signal Transducer and Activator of Transcription) Signal Mechanism; References.
505 8 _a7 Expansion of Stem Cells: Propagation of Animal Stem Cells Ex Vivo (In Culture)Abstract; 7.1 What Is Expansion and What Do We Expect from Expansion?; 7.2 Basic Concept-Ex Vivo Expansion of Hematopoietic Cells Today; 7.2.1 Molecules; 7.2.2 Distinct Stimuli; 7.2.3 Media for Expansion; 7.2.4 Hypoxia; References; 8 Stem Cell Pool: What Are the Best Patterns for Cellular Therapy?; Abstract; 8.1 Introduction; 8.2 Organogenesis from Adult Stem Cells and Problems with Different Tissues; 8.3 Therapeutic Implications for TCSCs as a New Concept; 8.4 The Concept of VSEL.
520 3 _aThis book provides a multifaceted look into the world of stem cells and explains the similarities and differences between plant and human stem cells. It explores the intersection between animals and plants and explains their cooperative role in bioengineering studies. The book treats both theoretical and practical aspects of stem cell research. It covers the advantages and limitations of many common applications related to stem cells: their sources, categories, engineering of these cells, reprogramming of their functions, and their role as novel cellular therapeutic approach. Written by experts in the field, the book focuses on aspects of stem cells ranging from expansion-propagation to metabolic reprogramming. It introduces the emergence of cancer stem cells and different modalities in targeted cancer stem cell therapies. It is a valuable source of fresh information for academics and researchers, examining molecular mechanisms of animal and plant stem cell regulation and their usage for therapeutic applications. Students at all levels of medical or engineering backgrounds will enjoy the case studies that illustrate and explain mechanisms, interactions, targeted effects, and multimodal therapeutic approaches. Academics, researchers, and professionals who want to expand their knowledge in this field will find this book an exceptional resource.
650 7 _aCélulas madre
_2embne
_0(OCoLC)fst01132975
_0
_9160528
700 1 _aRadotić, Ksenija,
_eautor
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-47763-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988 _aEBOOK, asignarmaterias, EBSPRINGER_2017B
998 _b02/2018
_dz
_e-
_zSI
999 _c95371
_d95371
_x1