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020			_a3319406280 _q(electronic bk.)
020			_a9783319406282 _q(electronic bk.)
020			_z3319406264
020			_z9783319406268 _q(print)
035			_a(OCoLC)971492041 _z(OCoLC)971593757 _z(OCoLC)971949017 _z(OCoLC)972102268 _z(OCoLC)972204257 _z(OCoLC)972461866 _z(OCoLC)972537225 _z(OCoLC)981868957 _z(OCoLC)1005757899 _z(OCoLC)1011796666
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050		4	_aRC377 _b2017 EB
245	0	0	_aHandbook of relapsing-remitting multiple sclerosis _cAaron Miller, editor.
264		1	_aCham, Switzerland _bAdis _c2017
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPreface; Contents; Contributors; Chapter 1: Multiple Sclerosis: An Overview; 1.1 Introduction; 1.2 Epidemiology and Risk Factors; References; Chapter 2: The Pathophysiology and Clinical Presentation of Multiple Sclerosis; 2.1 Introduction; 2.2 Etiology of Multiple Sclerosis; 2.2.1 Autoimmunity; 2.2.2 Genetics; 2.2.3 Infectious; 2.2.4 Degenerative; 2.3 Pathophysiologic Mechanisms of Multiple Sclerosis; 2.4 White Matter Plaque Formation; 2.5 Blood-Brain Barrier Breakdown, Leukocyte Entry, Demyelination, and Axonal Injury; 2.6 Cortical Demyelination.
505	8		_a2.7 Diffuse White Matter Changes, Global Atrophy, and Progressive Degeneration2.8 Remyelination and Repair; 2.9 The Clinical Presentation of Multiple Sclerosis; 2.10 Common Symptoms; 2.10.1 Fatigue; 2.10.2 Cognitive Dysfunction; 2.10.3 Mood Symptoms; 2.10.4 Optic Neuritis; 2.10.5 Brainstem and Cerebellar Symptoms; 2.10.6 Sensory Disturbances; 2.10.7 Motor Symptoms; 2.10.8 Bladder, Bowel, and Sexual Dysfunction; 2.11 Conclusion; References; Chapter 3: Assessment and Diagnosis of Relapsing Multiple Sclerosis; 3.1 Introduction.
505	8		_a3.2 Patient History and Clinical Relapses in Establishing a Diagnosis3.3 Role of MRI in Establishing a Diagnosis; 3.4 Patients Who Do Not Meet Full Diagnostic Criteria: Clinically Isolated Syndrome and Radiologically Isolated Syndrome; 3.4.1 Clinically Isolated Syndrome; 3.4.2 Radiologically Isolated Syndrome; 3.5 Role of Ancillary Testing in Establishing a Diagnosis (CSF Analysis and Evoked Potentials); 3.6 Assessment Scales; 3.7 Patient Counseling and Education; 3.8 Differential Diagnosis; 3.9 Neuromyelitis Optica Spectrum Disorders; 3.10 Acute Disseminated Encephalomyelitis; References.
505	8		_a5.2 New Monoclonal Antibodies5.2.1 Daclizumab; 5.2.2 Ocrelizumab; 5.3 Remyelination and Repair; 5.3.1 Anti-LINGO-1; 5.4 Stem Cell Therapeutics; 5.4.1 Hematopoietic Stem Cell Transplantation; 5.4.2 Mesenchymal Stem Cell Transplantation; Intravenous Mesenchymal Stem Cell Application; Intrathecal Mesenchymal Stem Cell Application; 5.4.3 Glial Progenitor Cell Transplantation; References; Chapter 6: Symptom Management in Multiple Sclerosis; 6.1 Introduction; 6.2 Fatigue; 6.3 Sensory Deficits and Pain; 6.4 Motor and Balance Issues; 6.5 Visual Deficits; 6.6 Bladder, Bowel, and Sexual Issues.
505	8		_aChapter 4: Treatment Strategies in Multiple Sclerosis4.1 Introduction; 4.2 Initiating Therapy; 4.3 Disease-Modifying Therapies; 4.3.1 Interferons; 4.3.2 Glatiramer Acetate; 4.3.3 Natalizumab; 4.3.4 Fingolimod; 4.3.5 Teriflunomide; 4.3.6 Dimethyl Fumarate; 4.3.7 Alemtuzumab; 4.3.8 Mitoxantrone; 4.4 Switching Disease-Modifying Therapies; 4.5 Acute Treatment of Relapses; 4.6 Treatment of Multiple Sclerosis During Pregnancy; 4.7 Treatment of Pediatric Multiple Sclerosis; 4.8 Conclusion; References; Chapter 5: Emerging Therapies in Multiple Sclerosis; 5.1 Introduction.
520	3		_aThis pocketbook is an evidence-based educational resource that provides a concise overview of diagnosis, treatment and long-term management of relapsing-remitting multiple sclerosis. An ideal clinical handbook for a wide range of medical professionals, this handbook includes international guidelines, clinically relevant clinical trial data, and an introduction to emerging therapies. Handbook of Relapsing-Remitting Multiple Sclerosis is a comprehensive overview of recent advances in this indication, enhanced by high quality figures and clinical images.
650		7	_aEsclerosis múltiple _2embne _0(OCoLC)fst01029018 _0 _9142007
700	1		_aMiller, Aaron E., _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-40628-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aSpringer_Medicine_2017
998			_b02/2018 _dz _e- _zSI
999			_c95322 _d95322 _x1