000			03770cam a2200433Ii 4500
999			_c95021 _d95021 _x1
001			95021
003			ES-MaUEC
005			20230102112643.0
006			m o d
007			cr cnu|||unuuu
008			161213s2017 sz o 001 0 eng d
020			_a3319447033 _q(electronic bk.)
020			_a9783319447032 _q(electronic bk.)
020			_z3319447017
020			_z9783319447018 _q(print)
035			_a(OCoLC)965825227 _z(OCoLC)966243544 _z(OCoLC)974649806 _z(OCoLC)981098862 _z(OCoLC)1005810180 _z(OCoLC)1011902423
040			_aN$T _cN$T _dIDEBK _dEBLCP _dGW5XE _dN$T _dYDX _dAZU _dMERUC _dUAB _dOCLCF _dCOO _dUPM _dIOG _dVT2 _dESU _dJBG _dIAD _dICW _dICN _dILO _dOTZ _dOCLCQ _dJG0 _dU3W _dES-MaUEC _bspa
050		4	_aQP86 _b.A345 2017 EB
245	0	0	_aAgeing : _blessons from C. elegans _cAnders Olsen, Matthew S. Gill, editors.
264		1	_aCham, Switzerland _bSpringer _c2017
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	0		_aHealthy ageing and longevity _vvolume 5
500			_aIncluye índice
500			_aSpringerLink
505	0		_aIntroduction -- Effects of aging on the basic biology and anatomy of C. elegans -- Dauer Formation and Ageing -- Longevity regulation by insulin/IGF-1 signaling -- Mitochondrial longevity pathways -- Influences of Germline Cells on Organismal Lifespan and Healthspan -- Reproductive Aging -- Nervous System Ageing -- Stress Response Pathways -- Oxidative Stress -- Genome stability and Protein homeostasis and ageing in C. elegans -- Translational control of longevity -- Lipid Metabolism, Lipid Signaling and Longevity -- Autophagy and ageing -- Dietary restriction in C. elegans -- Integration of metabolic signals -- Microbiota, Probiotic Bacteria and Ageing -- The Future of Worm Ageing.-Index.
520	3		_aThis book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans. With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public.
588	0		_aOnline resource; title from PDF title page (SpringerLink, viewed January 16, 2017).
988			_aEBOOK, EBSPRINGER_2017B
650		7	_aEnvejecimiento _2embne _9141231
700	1		_aGill, Matthew, _eeditor literario
700	1		_aOlsen, Anders, _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-44703-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI