000			04547cam a2200469Ii 4500
988			_aSpringer_Medicine_2017
999			_c95000 _d95000 _x1
001			95000
003			ES-MaUEC
005			20230102112642.0
006			m o d
007			cr cnu|||unuuu
008			161205t20162017gw o 001 0 eng d
020			_a3662529092 _q(electronic bk.)
020			_a9783662529096 _q(electronic bk.)
020			_z9783662529072 _q(print)
035			_a(OCoLC)965196110 _z(OCoLC)965773628
040			_aN$T _cN$T _dGW5XE _dEBLCP _dN$T _dYDX _dUAB _dIOG _dESU _dZ5A _dJBG _dIAD _dICN _dOTZ _dU3W _dES-MaUEC _bspa
050		4	_aRC606 _b2017 EB
245	0	0	_aPrimary immunodeficiency diseases : _bdefinition, diagnosis, and management _cNima Rezaei, Asghar Aghamohammadi, Luigi D. Notarangelo, editors.
250			_aSecond edition.
264		1	_aBerlin, Germany _bSpringer _c[2016]
264		4	_c2017
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
500			_aIncluye índice
500			_aSpringerLink
505	0		_aForeword; Preface; Contents; Contributors; 1: Introduction on Primary Immunodeficiency Diseases; 1.1 Definition; 1.1.1 Background; 1.1.2 History; 1.1.3 Epidemiology; 1.2 Etiology; 1.2.1 Classification; 1.2.2 Genetic Defects; 1.2.3 Pathophysiology; 1.3 Clinical Manifestations; 1.3.1 Infections; 1.3.2 Autoimmunity and Inflammatory Conditions; 1.3.3 Malignancies; 1.3.4 Other Manifestations; 1.4 Diagnosis; 1.4.1 Warning Signs and Symptoms; 1.4.2 Diagnostic Approach; 1.4.3 Approach to Laboratory Tests; 1.4.4 Phenotypic Approach; 1.5 Management; 1.5.1 General Considerations
505	8		_a1.5.2 Vaccination1.5.3 Antibiotics; 1.5.4 Immunoglobulin Replacement Therapy; 1.5.5 Transplantation; 1.5.6 Gene Therapy; 1.5.7 Adjunct Therapies; 1.5.8 Prevention; 1.5.9 Newborn Screening; References; 2: Combined T- and B-Cell Immunodeficiencies; 2.1 Introduction; 2.2 T-B+ Severe Combined Immunodeficiency; 2.2.1 Definition; 2.2.2 Etiology; 2.2.3 Clinical Manifestations; 2.2.4 Diagnosis; 2.2.5 Management; 2.3 T-B- Severe Combined Immunodeficiency; 2.3.1 Definition; 2.3.2 Etiology; 2.3.3 Clinical Manifestations; 2.3.4 Diagnosis; 2.3.5 Management; 2.4 Omenn Syndrome
505	8		_a2.12 Combined Immunodeficiencies with Immuno-Osseous Dysplasias2.12.1 Definition; 2.12.2 Etiology; 2.12.3 Clinical Manifestations; 2.12.4 Diagnosis; 2.12.5 Management; 2.13 Combined Immunodeficiency with Intestinal Atresias (TTC7A Deficiency); 2.13.1 Definition; 2.13.2 Etiology; 2.13.3 Clinical Manifestations; 2.13.4 Diagnosis; 2.13.5 Management; 2.14 MHC Class II Deficiency; 2.14.1 Definition; 2.14.2 Etiology; 2.14.3 Clinical Manifestations; 2.14.4 Diagnosis; 2.14.5 Management; 2.15 MHC Class I Deficiency; 2.15.1 Definition; 2.15.2 Etiology
505	8		_a2.4.1 Definition2.4.2 Etiology; 2.4.3 Clinical Manifestations; 2.4.4 Diagnosis; 2.4.5 Management; 2.5 Purine Salvage Pathway Defects; 2.5.1 Definition; 2.5.2 Etiology; 2.5.3 Clinical Manifestations; 2.5.4 Diagnosis; 2.5.5 Management; 2.6 AK2 Deficiency; 2.6.1 Definition; 2.6.2 Etiology; 2.6.3 Clinical Manifestations; 2.6.4 Diagnosis; 2.6.5 Management; 2.7 DOCK2 Deficiency; 2.7.1 Definition; 2.7.2 Etiology; 2.7.3 Clinical Manifestations; 2.7.4 Diagnosis; 2.7.5 Management; 2.8 Immunoglobulin Class Switch Recombination Deficiencies Affecting CD40-CD40L; 2.8.1 Definition
505	8		_a2.8.2 Etiology2.8.3 Clinical Manifestations; 2.8.4 Diagnosis; 2.8.5 Management; 2.9 Complete DiGeorge Syndrome; 2.9.1 Definition; 2.9.2 Etiology; 2.9.3 Clinical Manifestations; 2.9.4 Diagnosis; 2.9.5 Management; 2.10 CHARGE Syndrome; 2.10.1 Definition; 2.10.2 Etiology; 2.10.3 Clinical Manifestations; 2.10.4 Diagnosis; 2.10.5 Management; 2.11 Combined Immunodeficiency with Alopecia Totalis (WHN Deficiency); 2.11.1 Definition; 2.11.2 Etiology; 2.11.3 Clinical Manifestations; 2.11.4 Diagnosis; 2.11.5 Management
588	0		_aOnline resource; title from PDF title page (SpringerLink, viewed December 8, 2016).
650		7	_2embne _9142010 _aEnfermedades inmunológicas
700	1		_aAghamohammadi, Asghar, _eeditor literario
700	1		_aNotarangelo, Luigi, _eeditor literario
700	1		_aRezaei, Nima, _eeditor literario _988761
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-662-52909-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI