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007			cr |n|||||||||
008			161130s2017 sz ob 001 0 eng d
020			_a3319459236 _q(electronic bk.)
020			_a9783319459233 _q(electronic bk.)
020			_z331945921X
020			_z9783319459219
035			_a(OCoLC)964585792 _z(OCoLC)964931383 _z(OCoLC)970785671 _z(OCoLC)971038087 _z(OCoLC)974651721 _z(OCoLC)995767656 _z(OCoLC)1005757850
040			_aYDX _cYDX _dN$T _dGW5XE _dIDEBK _dOCLCF _dAZU _dN$T _dUAB _dCOO _dOCLCQ _dUPM _dIOG _dESU _dJBG _dIAD _dICW _dICN _dOTZ _dOCLCQ _dVT2 _dU3W _dOCLCA _dES-MaUEC _bspa
050		4	_aRM666.L57 _b2017 EB
245	0	4	_aThe science and practice of lithium therapy _cGin S. Malhi, Marc Masson, Frank Bellivier, editors.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2017
300			_a1 recurso en línea
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF _2rda
504			_aIncluye referencias bibliográficas e índice
505	0		_aSection I: Science of Lithium: The Ion : Lithium -- Pharmacokinetics and pharmacodynamics of lithium -- Lithium : neurotransmission and cellular mechanisms pathways underlying neuroprogression in bipolar disorder -- Lithium on gene expression modulation -- Neuroimaging and lithium -- Conclusion: overview of potential mechanisms of action of lithium in bipolar disorder -- Section II: Practice of Lithium Therapy -- Introduction of lithium in Medicine and Psychiatry -- Lithium Response variability -- Lithium Response variability: Pharmacogenomics studies -- Lithium Response variability: Biomarkers -- Lithium in acute and maintenance treatment of bipolar disorders -- Lithium and suicide prevention -- Lithium in Bipolar disorders international guidelines -- Lithium and pregnancy -- Lithium in children and adolescents -- Short and mid-term side effects of lithium -- Lithium, kidneys, renal failure -- Lithium intoxication -- Discontinuation and re-use of lithium -- Conclusion : overview of indications and monitoring of lithium in bipolar disorders.
520	3		_aThis book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide.
650		7	_aFarmacología _2embne _0(OCoLC)fst01000225 _0 _9137893
700	1		_aBellivier, Frank.
700	1		_aMalhi, Gin S.
700	1		_aMasson, Marc.
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-3-319-45923-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
988			_aSpringer_Medicine_2017
998			_b02/2018 _dz _e- _zSI
999			_c94950 _d94950 _x1